rdf:type |
|
lifeskim:mentions |
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pubmed:issue |
1
|
pubmed:dateCreated |
2009-12-16
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pubmed:abstractText |
Two serotonin 2A receptor (HTR2A) SNPs recently reported to be associated with antidepressant treatment response in STARD (rs7997012; rs1928040) were analyzed for association with treatment response in two independent Caucasian samples of patients with a Major Depressive Episode. In the combined sample (n=637) SNP rs7997012 was significantly associated with remission after five weeks providing first replicative support for the initial finding, with, however, an inverse allelic association as compared to the STARD sample.
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
pubmed:status |
MEDLINE
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pubmed:month |
Jan
|
pubmed:issn |
1873-7862
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pubmed:author |
|
pubmed:issnType |
Electronic
|
pubmed:volume |
20
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
65-8
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pubmed:meshHeading |
pubmed-meshheading:19758789-Adult,
pubmed-meshheading:19758789-Analysis of Variance,
pubmed-meshheading:19758789-Antidepressive Agents,
pubmed-meshheading:19758789-Depressive Disorder, Major,
pubmed-meshheading:19758789-Female,
pubmed-meshheading:19758789-Gene Frequency,
pubmed-meshheading:19758789-Genetic Predisposition to Disease,
pubmed-meshheading:19758789-Genome-Wide Association Study,
pubmed-meshheading:19758789-Genotype,
pubmed-meshheading:19758789-Humans,
pubmed-meshheading:19758789-Male,
pubmed-meshheading:19758789-Middle Aged,
pubmed-meshheading:19758789-Pharmacogenetics,
pubmed-meshheading:19758789-Polymorphism, Single Nucleotide,
pubmed-meshheading:19758789-Psychiatric Status Rating Scales,
pubmed-meshheading:19758789-Receptor, Serotonin, 5-HT2A
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pubmed:year |
2010
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pubmed:articleTitle |
HTR2A gene variation is involved in antidepressant treatment response.
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pubmed:affiliation |
Max Planck Institute of Psychiatry, Munich, Germany.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Multicenter Study
|