Linked Life Data

1975744

Source:http://linkedlifedata.com/resource/pubmed/id/1975744

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1990-10-16
pubmed:abstractText
We investigated the constitution of the vimentin regulatory region through the use of cloned deletion mutants and the nucleotide sequence analysis in order to determine the elements which are implicated in the various physiological stimulations. We report that the vimentin promoter is constituted of a juxtaposition of at least 20 different putative regulatory elements illustrating the molecular tinkering theory. Fifty-eight motifs were found, representing 20 different sequences. Each of these mini-elements displays a consensus sequence homologous to or closely related to that found in regulatory regions of different genes correlated with processes of cell activation and proliferation.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0926-5287
pubmed:author
pubmed:issnType
Print
pubmed:volume
30
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
423-9
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
Regulatory elements of the human vimentin gene: activation during proliferation.
pubmed:affiliation
Institut Pasteur, Paris, France.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't