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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
12
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pubmed:dateCreated |
2010-1-21
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pubmed:abstractText |
The natural course of hepatitis B virus (HBV) infection is likely related to host immune factors. Interleukin-18 (IL-18) plays a significant role in immune defense. This study was undertaken to determine the association between the presence of hepatocellular carcinoma (HCC) and single-nucleotide polymorphisms (SNPs) in the IL-18 gene in HBV-infected patients.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1573-2568
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pubmed:author |
pubmed-author:CheongHyun SubHS,
pubmed-author:CheongJae YounJY,
pubmed-author:ChoSung WonSW,
pubmed-author:HwangJae ChulJC,
pubmed-author:KimJin HongJH,
pubmed-author:KimYong SeokYS,
pubmed-author:KimmKuchanK,
pubmed-author:LeeJung AJA,
pubmed-author:LeeKee MyungKM,
pubmed-author:OhBermseokB,
pubmed-author:ParkByung LaeBL,
pubmed-author:ShinHyoung DooHD
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pubmed:copyrightInfo |
© Springer Science+Business Media, LLC 2009
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pubmed:issnType |
Electronic
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pubmed:volume |
54
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2722-8
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pubmed:meshHeading |
pubmed-meshheading:19757044-Adult,
pubmed-meshheading:19757044-Aged,
pubmed-meshheading:19757044-Aged, 80 and over,
pubmed-meshheading:19757044-Carcinoma, Hepatocellular,
pubmed-meshheading:19757044-Female,
pubmed-meshheading:19757044-Gene Frequency,
pubmed-meshheading:19757044-Genes, Reporter,
pubmed-meshheading:19757044-Genetic Predisposition to Disease,
pubmed-meshheading:19757044-Haplotypes,
pubmed-meshheading:19757044-Hep G2 Cells,
pubmed-meshheading:19757044-Hepatitis B, Chronic,
pubmed-meshheading:19757044-Humans,
pubmed-meshheading:19757044-Interleukin-18,
pubmed-meshheading:19757044-Linkage Disequilibrium,
pubmed-meshheading:19757044-Liver Cirrhosis,
pubmed-meshheading:19757044-Liver Neoplasms,
pubmed-meshheading:19757044-Logistic Models,
pubmed-meshheading:19757044-Male,
pubmed-meshheading:19757044-Middle Aged,
pubmed-meshheading:19757044-Odds Ratio,
pubmed-meshheading:19757044-Phenotype,
pubmed-meshheading:19757044-Polymorphism, Single Nucleotide,
pubmed-meshheading:19757044-Promoter Regions, Genetic,
pubmed-meshheading:19757044-Prospective Studies,
pubmed-meshheading:19757044-Republic of Korea,
pubmed-meshheading:19757044-Risk Assessment,
pubmed-meshheading:19757044-Risk Factors,
pubmed-meshheading:19757044-Transfection
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pubmed:year |
2009
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pubmed:articleTitle |
A functional SNP of the Interleukin-18 gene is associated with the presence of hepatocellular carcinoma in hepatitis B virus-infected patients.
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pubmed:affiliation |
Department of Biochemistry and Molecular Biology, Hanyang University College of Medicine, Seoul, South Korea.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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