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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2010-1-21
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pubmed:abstractText |
Exendin-4 is a 39 amino acid agonist of the glucagon-like peptide receptor and has been approved for treatment of type 2 diabetes. Many reports describe an increased incidence of acute pancreatitis in humans treated with exendin-4 (exenatide). Previous studies have evaluated the effect of exendin-4 on beta cells and beta cell function. We evaluated the histological and biochemical effects of exendin-4 on the pancreas in rats.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Adipokines,
http://linkedlifedata.com/resource/pubmed/chemical/Alanine Transaminase,
http://linkedlifedata.com/resource/pubmed/chemical/Amylases,
http://linkedlifedata.com/resource/pubmed/chemical/Aspartate Aminotransferases,
http://linkedlifedata.com/resource/pubmed/chemical/Blood Glucose,
http://linkedlifedata.com/resource/pubmed/chemical/Hypoglycemic Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Insulin,
http://linkedlifedata.com/resource/pubmed/chemical/Lipase,
http://linkedlifedata.com/resource/pubmed/chemical/Peptides,
http://linkedlifedata.com/resource/pubmed/chemical/Venoms,
http://linkedlifedata.com/resource/pubmed/chemical/exenatide
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1432-0428
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
53
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
153-9
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:19756486-Adipokines,
pubmed-meshheading:19756486-Alanine Transaminase,
pubmed-meshheading:19756486-Amylases,
pubmed-meshheading:19756486-Animals,
pubmed-meshheading:19756486-Aspartate Aminotransferases,
pubmed-meshheading:19756486-Blood Glucose,
pubmed-meshheading:19756486-Body Weight,
pubmed-meshheading:19756486-Humans,
pubmed-meshheading:19756486-Hypoglycemic Agents,
pubmed-meshheading:19756486-Insulin,
pubmed-meshheading:19756486-Lipase,
pubmed-meshheading:19756486-Male,
pubmed-meshheading:19756486-Pancreas,
pubmed-meshheading:19756486-Pancreatitis,
pubmed-meshheading:19756486-Peptides,
pubmed-meshheading:19756486-Rats,
pubmed-meshheading:19756486-Rats, Sprague-Dawley,
pubmed-meshheading:19756486-Venoms
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pubmed:year |
2010
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pubmed:articleTitle |
Biochemical and histological effects of exendin-4 (exenatide) on the rat pancreas.
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pubmed:affiliation |
Division of Gastroenterology and Hepatology, University of Missouri Kansas City, Kansas City, MO 64108, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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