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rdf:type |
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lifeskim:mentions |
umls-concept:C0007732,
umls-concept:C0009491,
umls-concept:C0014118,
umls-concept:C0026336,
umls-concept:C0034493,
umls-concept:C0038172,
umls-concept:C0038404,
umls-concept:C0042313,
umls-concept:C0080194,
umls-concept:C0205314,
umls-concept:C0332325,
umls-concept:C0441655,
umls-concept:C0663241,
umls-concept:C0679622,
umls-concept:C1515655,
umls-concept:C1579762,
umls-concept:C2001521
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pubmed:issue |
12
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pubmed:dateCreated |
2009-11-17
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pubmed:abstractText |
We assessed the in vitro and in vivo efficacy of the novel parenteral broad-spectrum cephalosporin ceftaroline against Enterococcus faecalis in time-kill experiments and in a rabbit endocarditis model with simulated human dosing. Ceftaroline was more active than either vancomycin or linezolid against vancomycin-sensitive and -resistant isolates of E. faecalis.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/19752276-11502515,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19752276-11557476,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19752276-12435665,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19752276-1416824,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19752276-1423219,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19752276-16048970,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19752276-16239290,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19752276-17591849,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19752276-18625769,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19752276-4111329,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19752276-5123055,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19752276-7447427,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19752276-9608855
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1098-6596
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
53
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
5300-2
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pubmed:dateRevised |
2010-9-27
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pubmed:meshHeading |
pubmed-meshheading:19752276-Acetamides,
pubmed-meshheading:19752276-Animals,
pubmed-meshheading:19752276-Anti-Bacterial Agents,
pubmed-meshheading:19752276-Cephalosporins,
pubmed-meshheading:19752276-Endocarditis, Bacterial,
pubmed-meshheading:19752276-Enterococcus faecalis,
pubmed-meshheading:19752276-Methicillin-Resistant Staphylococcus aureus,
pubmed-meshheading:19752276-Microbial Sensitivity Tests,
pubmed-meshheading:19752276-Oxazolidinones,
pubmed-meshheading:19752276-Rabbits,
pubmed-meshheading:19752276-Vancomycin,
pubmed-meshheading:19752276-Vancomycin Resistance
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pubmed:year |
2009
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pubmed:articleTitle |
In vivo activity of a novel anti-methicillin-resistant Staphylococcus aureus cephalosporin, ceftaroline, against vancomycin-susceptible and -resistant Enterococcus faecalis strains in a rabbit endocarditis model: a comparative study with linezolid and vancomycin.
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pubmed:affiliation |
Université de Nantes, Nantes Atlantique Universités, Thérapeutiques Cliniques et Expérimentales des Infections, UFR Médecine, Nantes, France.
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pubmed:publicationType |
Journal Article,
Comparative Study
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