Linked Life Data

19751890

Source:http://linkedlifedata.com/resource/pubmed/id/19751890

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2009-9-15
pubmed:abstractText
An expanding proportion of people in the United States and worldwide are affected by kidney disease, leading to a growing concern over the public health implications. Despite the high prevalence and the considerable associated health risks of kidney disease, major gaps in our knowledge base hinder the delivery of optimal medical care to affected individuals. Moreover, research progress that translates into clinical benefit has been slow. For example, over the past 20 years, there has been no successful implementation of a new therapeutic agent specifically designed for the treatment of glomerular diseases, which in part explains why glomerular diseases remain the leading cause of kidney disease in the United States and worldwide. Similarly, the limitations of current approaches to dialysis as treatment of end-stage kidney disease are becoming more apparent, with marginal improvements in risks for hospitalization or mortality over time. Along with recognition of changes in the public health burden of kidney disease, and perception of limited progress in the clinical treatment of kidney disease, a change in kidney disease research is now underway. We are entering a new era in biomedicine emphasizing interdisciplinary and translational research. We here delineate the purpose, mission, and goals, and describe the evolving vision, infrastructure, and research platform of a new Kidney Research Institute, designed to overcome barriers to researching improvements in effective clinical care.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
1558-4488
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
29
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
457-66
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Creating research infrastructure and functionality to address chronic kidney disease: the Kidney Research Institute.
pubmed:affiliation
Division of Nephrology, Department of Medicine, University of Washington School of Medicine, Seattle, WA, USA. himmej@u.washington.edu
pubmed:publicationType
Journal Article, Comment, Review