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rdf:type |
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lifeskim:mentions |
umls-concept:C0004083,
umls-concept:C0006267,
umls-concept:C0025664,
umls-concept:C0026882,
umls-concept:C0030705,
umls-concept:C0205221,
umls-concept:C0205314,
umls-concept:C0600260,
umls-concept:C0679622,
umls-concept:C1367657,
umls-concept:C1418544,
umls-concept:C1527148,
umls-concept:C1709016,
umls-concept:C2603343
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pubmed:issue |
1-2
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pubmed:dateCreated |
2010-1-27
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pubmed:abstractText |
The aim of our study was to determine the genetic risk conferred by SNPs in the SERPINA1 and ADRB2 for development of Chronic Obstructive Pulmonary Disease (COPD) and Disseminated Bronchiectasis (DB), while at the same time validating the NanoChip technology. This was a case-control study consisting of 112 COPD, 62 DB patients and 2 control groups (106 smokers without COPD: healthy smokers control group and 205 general population subjects).
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1873-2933
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pubmed:author |
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pubmed:copyrightInfo |
Copyright 2009 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:volume |
43
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
43-50
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pubmed:meshHeading |
pubmed-meshheading:19747908-Adult,
pubmed-meshheading:19747908-Aged,
pubmed-meshheading:19747908-Aged, 80 and over,
pubmed-meshheading:19747908-Bronchiectasis,
pubmed-meshheading:19747908-Case-Control Studies,
pubmed-meshheading:19747908-European Continental Ancestry Group,
pubmed-meshheading:19747908-Female,
pubmed-meshheading:19747908-Genetic Predisposition to Disease,
pubmed-meshheading:19747908-Genotype,
pubmed-meshheading:19747908-Greece,
pubmed-meshheading:19747908-Humans,
pubmed-meshheading:19747908-Male,
pubmed-meshheading:19747908-Microarray Analysis,
pubmed-meshheading:19747908-Middle Aged,
pubmed-meshheading:19747908-Mutation,
pubmed-meshheading:19747908-Polymorphism, Genetic,
pubmed-meshheading:19747908-Pulmonary Disease, Chronic Obstructive,
pubmed-meshheading:19747908-Receptors, Adrenergic, beta-2,
pubmed-meshheading:19747908-Risk Factors,
pubmed-meshheading:19747908-alpha 1-Antitrypsin
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pubmed:year |
2010
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pubmed:articleTitle |
Development of novel microarray methodology for the study of mutations in the SERPINA1 and ADRB2 genes--their association with Obstructive Pulmonary Disease and Disseminated Bronchiectasis in Greek patients.
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pubmed:affiliation |
Department of Medical Genetics, Medical School, University of Athens, Thivon and Levadias, 11257 Athens, Greece. atpapath@med.uoa.gr
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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