Linked Life Data

19746931

Source:http://linkedlifedata.com/resource/pubmed/id/19746931

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10
pubmed:dateCreated
2010-12-14
pubmed:abstractText
We propose a new approach to optical virus detection based on the spatial assembly of gold nanoparticles on the surface of viruses. Since JC virus-like particles (VLPs) comprise a repeating viral capsid protein that binds to sialic acid, the conjugation of sialic acid-linked Au particles with VLPs enables the spatial arrangement of Au particles on the VLP surface. This structure produced a red shift in the absorption spectrum due to plasmon coupling between adjacent Au particles, leading to the construction of an optical virus detection system. Our system depends not on the simple cross-linking of VLPs and Au particles, but on an ordered Au structure covering the entire surface of the VLPs and can be applied to various virus detection systems using the inherent ligand recognition of animal viruses.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
1520-4812
pubmed:author
pubmed:issnType
Electronic
pubmed:day
21
pubmed:volume
20
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1848-52
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Gold nanoparticle arrangement on viral particles through carbohydrate recognition: a non-cross-linking approach to optical virus detection.
pubmed:affiliation
Graduate School of Science and Research Institute for Electronic Science, Hokkaido University, Sapporo, Japan. kniikura@poly.es.hokudai.ac.jp
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't