Linked Life Data

19746368

Source:http://linkedlifedata.com/resource/pubmed/id/19746368

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
40
pubmed:dateCreated
2009-10-14
pubmed:abstractText
Di- and multiazole-substituted fluorocyclic products (2-13) were readily synthesized in good to high yields. These were synthesized by nucleophilic substitution reactions of perfluorocycloalkenes with azoles (i.e., imidazole, triazole) involving simple reaction procedures. Interestingly, these azoles were later found to be reactive not only with the vinylic, but also with the allylic fluorine atoms. This resulted in the substitution of up to six azoles on the fluorinated rings. Stoichiometry plays a key role in determining the degree of substitution. For comparison, the analogous reactions of N-substituted 1-(trimethylsilyl)-imidazole and 1-(trimethylsilyl)-1,2,4-triazole were also investigated. All of the new compounds were fully characterized by elemental, spectral ((19)F, (1)H, (13)C NMR), and thermal differential scanning calorimetry (DSC) analyses.
pubmed:language
eng
pubmed:journal
pubmed:status
PubMed-not-MEDLINE
pubmed:month
Oct
pubmed:issn
1521-3765
pubmed:author
pubmed:issnType
Electronic
pubmed:day
12
pubmed:volume
15
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
10554-62
pubmed:year
2009
pubmed:articleTitle
Azoles as reactive nucleophiles with cyclic perfluoroalkenes.
pubmed:affiliation
Department of Chemistry, University of Idaho, Moscow, D 83844-2343, USA.
pubmed:publicationType
Journal Article