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rdf:type |
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lifeskim:mentions |
umls-concept:C0008976,
umls-concept:C0038454,
umls-concept:C0087111,
umls-concept:C0199176,
umls-concept:C0201950,
umls-concept:C0301630,
umls-concept:C0360714,
umls-concept:C0428466,
umls-concept:C0580822,
umls-concept:C1274040,
umls-concept:C1547300,
umls-concept:C1548760,
umls-concept:C1550594
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pubmed:issue |
11
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pubmed:dateCreated |
2009-10-27
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pubmed:abstractText |
Laboratory experiments suggest statins reduce stroke severity and improve outcomes. The Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) trial was a placebo-controlled, randomized trial designed to determine whether treatment with atorvastatin reduces strokes in subjects with recent stroke or transient ischemic attack (n=4731). We analyzed SPARCL trial data to determine whether treatment favorably shifts the distribution of severities of ischemic cerebrovascular outcomes.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1524-4628
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pubmed:author |
pubmed-author:AltafullahIrfanI,
pubmed-author:AmarencoPierreP,
pubmed-author:CallahanAlfredA,
pubmed-author:GoldsteinLarry BLB,
pubmed-author:HennericiMichaelM,
pubmed-author:MacLeodMary JMJ,
pubmed-author:MessigMichaelM,
pubmed-author:MichaelKK,
pubmed-author:SillesenHenrikH,
pubmed-author:Stroke Prevention by Aggressive Reduction in Cholesterol Levels ...,
pubmed-author:WelchAA,
pubmed-author:ZivinJustinJ,
pubmed-author:ZweiflerRichardR
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pubmed:issnType |
Electronic
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pubmed:volume |
40
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3526-31
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pubmed:dateRevised |
2010-3-4
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pubmed:meshHeading |
pubmed-meshheading:19745172-Aged,
pubmed-meshheading:19745172-Cholesterol,
pubmed-meshheading:19745172-Double-Blind Method,
pubmed-meshheading:19745172-Female,
pubmed-meshheading:19745172-Follow-Up Studies,
pubmed-meshheading:19745172-Humans,
pubmed-meshheading:19745172-Hydroxymethylglutaryl-CoA Reductase Inhibitors,
pubmed-meshheading:19745172-Hypercholesterolemia,
pubmed-meshheading:19745172-Male,
pubmed-meshheading:19745172-Middle Aged,
pubmed-meshheading:19745172-Stroke,
pubmed-meshheading:19745172-Treatment Outcome
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pubmed:year |
2009
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pubmed:articleTitle |
Statin treatment and stroke outcome in the Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) trial.
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pubmed:affiliation |
Department of Medicine, Division of Neurology, Duke University Medical Center, Durham, NC 27710, USA. golds004@mc.duke.edu
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pubmed:publicationType |
Journal Article,
Comparative Study,
Randomized Controlled Trial,
Controlled Clinical Trial,
Research Support, Non-U.S. Gov't
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