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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
9
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pubmed:dateCreated |
2009-10-23
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pubmed:abstractText |
TBX1 encodes a T-box transcription factor implicated in DiGeorge syndrome, which affects the development of many organs, including the heart. Loss of Tbx1 results into hypoplasia of heart regions derived from the second heart field, a population of cardiac progenitors cells (CPCs). Thus, we hypothesized that Tbx1 is an important player in the biology of CPCs.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1524-4571
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
23
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pubmed:volume |
105
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
842-51
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pubmed:dateRevised |
2010-12-3
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pubmed:meshHeading |
pubmed-meshheading:19745164-Animals,
pubmed-meshheading:19745164-Cell Differentiation,
pubmed-meshheading:19745164-Cell Line,
pubmed-meshheading:19745164-Cell Lineage,
pubmed-meshheading:19745164-Cell Proliferation,
pubmed-meshheading:19745164-Endothelial Cells,
pubmed-meshheading:19745164-Mice,
pubmed-meshheading:19745164-Mice, Knockout,
pubmed-meshheading:19745164-Mice, Transgenic,
pubmed-meshheading:19745164-Mitosis,
pubmed-meshheading:19745164-Multipotent Stem Cells,
pubmed-meshheading:19745164-Muscle, Smooth, Vascular,
pubmed-meshheading:19745164-Myocytes, Cardiac,
pubmed-meshheading:19745164-Myocytes, Smooth Muscle,
pubmed-meshheading:19745164-Protein Binding,
pubmed-meshheading:19745164-Serum Response Factor,
pubmed-meshheading:19745164-Signal Transduction,
pubmed-meshheading:19745164-T-Box Domain Proteins,
pubmed-meshheading:19745164-Transfection
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pubmed:year |
2009
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pubmed:articleTitle |
Tbx1 regulates proliferation and differentiation of multipotent heart progenitors.
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pubmed:affiliation |
Institute of Biosciences and Technology, Texas A&M University Health Science Center, Houston, TX, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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