|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
10
|
|
pubmed:dateCreated |
2009-11-5
|
|
pubmed:abstractText |
The efficacy of temozolomide (TMZ) or dacarbazine (DTIC) in melanoma treatment depends on low O-6-methylguanine-DNA-methyltransferase (MGMT) repair and on high mismatch repair. The aim of this study was to identify individual host markers for hematologic side effects and the treatment efficacy of TMZ or DTIC in melanoma treatment.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Adaptor Proteins, Signal Transducing,
http://linkedlifedata.com/resource/pubmed/chemical/Antineoplastic Agents, Alkylating,
http://linkedlifedata.com/resource/pubmed/chemical/DNA, Neoplasm,
http://linkedlifedata.com/resource/pubmed/chemical/Dacarbazine,
http://linkedlifedata.com/resource/pubmed/chemical/MLH1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/MSH2 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/MutS Homolog 2 Protein,
http://linkedlifedata.com/resource/pubmed/chemical/Nuclear Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/O(6)-Methylguanine-DNA...,
http://linkedlifedata.com/resource/pubmed/chemical/temozolomide
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Oct
|
|
pubmed:issn |
1744-6872
|
|
pubmed:author |
pubmed-author:BoeckmannLarsL,
pubmed-author:BrockmoellerJuergenJ,
pubmed-author:DIASA G de SAG,
pubmed-author:EmmertSteffenS,
pubmed-author:GutzmerRalfR,
pubmed-author:KunzManfredM,
pubmed-author:KuschalChristianeC,
pubmed-author:LaspePetraP,
pubmed-author:RosenbergerAlbertA,
pubmed-author:SchirmerMarkusM,
pubmed-author:SchoenMichael PMP,
pubmed-author:StrueverDianaD,
pubmed-author:ThomsKai-MartinKM
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
19
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
760-9
|
|
pubmed:meshHeading |
pubmed-meshheading:19741564-Adaptor Proteins, Signal Transducing,
pubmed-meshheading:19741564-Adult,
pubmed-meshheading:19741564-Aged,
pubmed-meshheading:19741564-Aged, 80 and over,
pubmed-meshheading:19741564-Antineoplastic Agents, Alkylating,
pubmed-meshheading:19741564-DNA, Neoplasm,
pubmed-meshheading:19741564-DNA Repair,
pubmed-meshheading:19741564-Dacarbazine,
pubmed-meshheading:19741564-European Continental Ancestry Group,
pubmed-meshheading:19741564-Female,
pubmed-meshheading:19741564-Humans,
pubmed-meshheading:19741564-Male,
pubmed-meshheading:19741564-Melanoma,
pubmed-meshheading:19741564-Middle Aged,
pubmed-meshheading:19741564-MutS Homolog 2 Protein,
pubmed-meshheading:19741564-Nuclear Proteins,
pubmed-meshheading:19741564-O(6)-Methylguanine-DNA Methyltransferase,
pubmed-meshheading:19741564-Tumor Cells, Cultured
|
|
pubmed:year |
2009
|
|
pubmed:articleTitle |
Effect of DNA repair host factors on temozolomide or dacarbazine melanoma treatment in Caucasians.
|
|
pubmed:affiliation |
Department of Dermatology, Georg-August-University Goettingen, Germany. semmert@gwdg.de
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
