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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2009-12-23
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pubmed:abstractText |
The tuberomammillary histaminergic neurons are involved in the sedative component of anesthetic action. The nucleus basalis magnocellularis (NBM) in the basal forebrain receives dense excitatory innervation from the tuberomammillary nucleus and is recognized as an important site of sleep-wake regulation. This study investigated whether NBM administration of histaminergic drugs may modulate arousal/emergence from isoflurane anesthesia.
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pubmed:grant |
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1528-1175
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
111
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
725-33
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pubmed:meshHeading |
pubmed-meshheading:19741500-Anesthesia, Inhalation,
pubmed-meshheading:19741500-Anesthesia Recovery Period,
pubmed-meshheading:19741500-Anesthetics, Inhalation,
pubmed-meshheading:19741500-Animals,
pubmed-meshheading:19741500-Arousal,
pubmed-meshheading:19741500-Basal Nucleus of Meynert,
pubmed-meshheading:19741500-Behavior, Animal,
pubmed-meshheading:19741500-Electroencephalography,
pubmed-meshheading:19741500-Histamine,
pubmed-meshheading:19741500-Histamine H1 Antagonists,
pubmed-meshheading:19741500-Histamine H2 Antagonists,
pubmed-meshheading:19741500-Injections,
pubmed-meshheading:19741500-Isoflurane,
pubmed-meshheading:19741500-Male,
pubmed-meshheading:19741500-Motor Activity,
pubmed-meshheading:19741500-Rats,
pubmed-meshheading:19741500-Rats, Long-Evans,
pubmed-meshheading:19741500-Respiratory Mechanics,
pubmed-meshheading:19741500-Synaptic Transmission
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pubmed:year |
2009
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pubmed:articleTitle |
Basal forebrain histaminergic transmission modulates electroencephalographic activity and emergence from isoflurane anesthesia.
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pubmed:affiliation |
Department of Physiology and Pharmacology, Program in Neuroscience, The University of Western Ontario, London, Ontario, Canada.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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