Linked Life Data

19741497

Source:http://linkedlifedata.com/resource/pubmed/id/19741497

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2009-12-23
pubmed:abstractText
Some anesthetics have been suggested to induce neurotoxicity, including promotion of Alzheimer's disease neuropathogenesis. Nitrous oxide and isoflurane are common anesthetics. The authors set out to assess the effects of nitrous oxide and/or isoflurane on apoptosis and beta-amyloid (Abeta) levels in H4 human neuroglioma cells and primary neurons from naïve mice.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
http://linkedlifedata.com/resource/pubmed/chemical/Actins, http://linkedlifedata.com/resource/pubmed/chemical/Amyloid Precursor Protein Secretases, http://linkedlifedata.com/resource/pubmed/chemical/Amyloid beta-Peptides, http://linkedlifedata.com/resource/pubmed/chemical/Amyloid beta-Protein Precursor, http://linkedlifedata.com/resource/pubmed/chemical/Anesthetics, Inhalation, http://linkedlifedata.com/resource/pubmed/chemical/Carbamates, http://linkedlifedata.com/resource/pubmed/chemical/Caspase 3, http://linkedlifedata.com/resource/pubmed/chemical/Dipeptides, http://linkedlifedata.com/resource/pubmed/chemical/Enzyme Inhibitors, http://linkedlifedata.com/resource/pubmed/chemical/Isoflurane, http://linkedlifedata.com/resource/pubmed/chemical/L 685458, http://linkedlifedata.com/resource/pubmed/chemical/Nitrous Oxide
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
1528-1175
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
111
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
741-52
pubmed:dateRevised
2010-12-3
pubmed:meshHeading
pubmed-meshheading:19741497-Actins, pubmed-meshheading:19741497-Amyloid Precursor Protein Secretases, pubmed-meshheading:19741497-Amyloid beta-Peptides, pubmed-meshheading:19741497-Amyloid beta-Protein Precursor, pubmed-meshheading:19741497-Anesthetics, Inhalation, pubmed-meshheading:19741497-Animals, pubmed-meshheading:19741497-Apoptosis, pubmed-meshheading:19741497-Blotting, Western, pubmed-meshheading:19741497-Carbamates, pubmed-meshheading:19741497-Caspase 3, pubmed-meshheading:19741497-Cell Line, Tumor, pubmed-meshheading:19741497-Dipeptides, pubmed-meshheading:19741497-Enzyme Activation, pubmed-meshheading:19741497-Enzyme Inhibitors, pubmed-meshheading:19741497-Enzyme-Linked Immunosorbent Assay, pubmed-meshheading:19741497-Humans, pubmed-meshheading:19741497-In Situ Nick-End Labeling, pubmed-meshheading:19741497-Isoflurane, pubmed-meshheading:19741497-Mice, pubmed-meshheading:19741497-Neurons, pubmed-meshheading:19741497-Nitrous Oxide
pubmed:year
2009
pubmed:articleTitle
Nitrous oxide plus isoflurane induces apoptosis and increases beta-amyloid protein levels.
pubmed:affiliation
Department of Anesthesia, Critical Care and Pain Medicine, Genetics and Aging Research Unit, MassGeneral Institute for Neurodegenerative Disease, Massachusetts General Hospital and Harvard Medical School, 114 16th Street, Charlestown, MA 02129, USA.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural