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rdf:type |
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lifeskim:mentions |
umls-concept:C0036525,
umls-concept:C0051755,
umls-concept:C0296263,
umls-concept:C0332293,
umls-concept:C0677930,
umls-concept:C0681842,
umls-concept:C0995188,
umls-concept:C1274040,
umls-concept:C1515670,
umls-concept:C1522484,
umls-concept:C1527249
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pubmed:issue |
30
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pubmed:dateCreated |
2009-10-19
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pubmed:abstractText |
To study the power of the epidermal growth factor receptor (EGFR) epiregulin (EREG) and amphiregulin (AREG) ligands' expression in primary tumors to predict the outcome in patients with chemorefractory metastatic colorectal cancer (cmCRC) treated with the combination of cetuximab and irinotecan.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Monoclonal,
http://linkedlifedata.com/resource/pubmed/chemical/Antineoplastic Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Camptothecin,
http://linkedlifedata.com/resource/pubmed/chemical/Epidermal Growth Factor,
http://linkedlifedata.com/resource/pubmed/chemical/Glycoproteins,
http://linkedlifedata.com/resource/pubmed/chemical/Intercellular Signaling Peptides...,
http://linkedlifedata.com/resource/pubmed/chemical/KRAS protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Ligands,
http://linkedlifedata.com/resource/pubmed/chemical/Proto-Oncogene Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/Receptor, Epidermal Growth Factor,
http://linkedlifedata.com/resource/pubmed/chemical/amphiregulin,
http://linkedlifedata.com/resource/pubmed/chemical/cetuximab,
http://linkedlifedata.com/resource/pubmed/chemical/epiregulin,
http://linkedlifedata.com/resource/pubmed/chemical/irinotecan,
http://linkedlifedata.com/resource/pubmed/chemical/ras Proteins
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1527-7755
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pubmed:author |
pubmed-author:BiesmansBartB,
pubmed-author:De HertoghGertG,
pubmed-author:De RoockWendyW,
pubmed-author:De SchutterJefJ,
pubmed-author:FieuwsSteffenS,
pubmed-author:HumbletYvesY,
pubmed-author:JacobsBartB,
pubmed-author:Laurent-PuigPierreP,
pubmed-author:Pénault-LlorcaFrederiqueF,
pubmed-author:PeetersMarcM,
pubmed-author:PiessevauxHubertH,
pubmed-author:TejparSabineS,
pubmed-author:Van CutsemEricE,
pubmed-author:Van LaethemJean-LucJL,
pubmed-author:Van OirbeekRobinR,
pubmed-author:VandesompeleJoJ
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pubmed:issnType |
Electronic
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pubmed:day |
20
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pubmed:volume |
27
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
5068-74
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pubmed:dateRevised |
2010-4-9
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pubmed:meshHeading |
pubmed-meshheading:19738126-Antibodies, Monoclonal,
pubmed-meshheading:19738126-Antineoplastic Agents,
pubmed-meshheading:19738126-Camptothecin,
pubmed-meshheading:19738126-Cohort Studies,
pubmed-meshheading:19738126-Colorectal Neoplasms,
pubmed-meshheading:19738126-Epidermal Growth Factor,
pubmed-meshheading:19738126-Gene Expression,
pubmed-meshheading:19738126-Glycoproteins,
pubmed-meshheading:19738126-Humans,
pubmed-meshheading:19738126-Intercellular Signaling Peptides and Proteins,
pubmed-meshheading:19738126-Ligands,
pubmed-meshheading:19738126-Prognosis,
pubmed-meshheading:19738126-Proto-Oncogene Proteins,
pubmed-meshheading:19738126-RNA, Messenger,
pubmed-meshheading:19738126-Receptor, Epidermal Growth Factor,
pubmed-meshheading:19738126-Survival Analysis,
pubmed-meshheading:19738126-ras Proteins
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pubmed:year |
2009
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pubmed:articleTitle |
Amphiregulin and epiregulin mRNA expression in primary tumors predicts outcome in metastatic colorectal cancer treated with cetuximab.
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pubmed:affiliation |
Department of Pathology, Digestive Oncology Unit, University Hospital Gasthuisberg, Katholieke Universiteit Leuven, Leuven, Belgium.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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