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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2009-12-23
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pubmed:abstractText |
Chronic hypoxia in the kidney has been suggested as a final common pathway to end-stage renal disease. Hypoxia-inducible factor (HIF) is a transcription factor that regulates cellular hypoxic responses, and it is a promising target with therapeutic potential in various kidney disease models. In this study, we investigated whether HIF activation could attenuate renal injury in the rat remnant kidney model.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1460-2385
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
25
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
77-85
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pubmed:meshHeading |
pubmed-meshheading:19737871-Amino Acids, Dicarboxylic,
pubmed-meshheading:19737871-Animals,
pubmed-meshheading:19737871-Chronic Disease,
pubmed-meshheading:19737871-Disease Models, Animal,
pubmed-meshheading:19737871-Disease Progression,
pubmed-meshheading:19737871-Glucose Transporter Type 1,
pubmed-meshheading:19737871-Hypoxia-Inducible Factor 1,
pubmed-meshheading:19737871-Kidney,
pubmed-meshheading:19737871-Kidney Diseases,
pubmed-meshheading:19737871-Male,
pubmed-meshheading:19737871-Nephrectomy,
pubmed-meshheading:19737871-Oxidative Stress,
pubmed-meshheading:19737871-Rats,
pubmed-meshheading:19737871-Rats, Sprague-Dawley,
pubmed-meshheading:19737871-Vascular Endothelial Growth Factor A
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pubmed:year |
2010
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pubmed:articleTitle |
Activation of hypoxia-inducible factor attenuates renal injury in rat remnant kidney.
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pubmed:affiliation |
Department of Internal Medicine and Kidney Research Institute, Hallym University College of Medicine, Anyang, Korea.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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