Linked Life Data

19736513

Source:http://linkedlifedata.com/resource/pubmed/id/19736513

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2009-12-1
pubmed:abstractText
Collective migration of adherent cohorts of cells is a common and crucial phenomenon during embryonic development and adult tissue homeostasis. The zebrafish posterior lateral line primordium has emerged as a powerful in vivo model to study collective migration due to its relative simplicity and accessibility. While it has become clear that chemokine signaling is the primary guidance system responsible for directing the primordium along its migratory path it is not clear what mechanisms downstream of chemokine signaling coordinate migration of individual cells within the primordium. In this review, we summarize the cell signaling interactions that underlie collective migration of the primordium and discuss proposed mechanisms for the function of chemokine signaling in this tissue.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
1933-6926
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
3
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
365-8
pubmed:dateRevised
2010-12-7
pubmed:meshHeading
pubmed:articleTitle
Multiple signaling interactions coordinate collective cell migration of the posterior lateral line primordium.
pubmed:affiliation
Neurobiology and Anatomy Department, University of Utah, Salt Lake City, UT 84132, USA. piotrowski@neuro.utah.edu
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, Non-P.H.S., Review, Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural