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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4 Pt 2
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pubmed:dateCreated |
2009-12-9
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pubmed:abstractText |
Poor response to antipsychotics is still an important problem in the treatment of many schizophrenia patients. N-acetylcysteine (NAC) is a compound that exerts anti-oxidant and scavenging actions against reactive oxygen species. This paper reports a case of poorly responsive schizophrenia patient who improved considerably with add-on NAC 600 mg/day. The NAC might work through activating cysteine-glutamate antiporters or reducing in nitric oxide (NO) metabolites, free radicals and cytokines or through both of these mechanisms.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1814-1412
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
626-8
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pubmed:meshHeading |
pubmed-meshheading:19735056-Acetylcysteine,
pubmed-meshheading:19735056-Adult,
pubmed-meshheading:19735056-Antipsychotic Agents,
pubmed-meshheading:19735056-Benzodiazepines,
pubmed-meshheading:19735056-Clopenthixol,
pubmed-meshheading:19735056-Delayed-Action Preparations,
pubmed-meshheading:19735056-Dose-Response Relationship, Drug,
pubmed-meshheading:19735056-Drug Resistance,
pubmed-meshheading:19735056-Drug Therapy, Combination,
pubmed-meshheading:19735056-Female,
pubmed-meshheading:19735056-Free Radical Scavengers,
pubmed-meshheading:19735056-Humans,
pubmed-meshheading:19735056-Psychiatric Status Rating Scales,
pubmed-meshheading:19735056-Schizophrenia,
pubmed-meshheading:19735056-Schizophrenic Psychology
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pubmed:year |
2009
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pubmed:articleTitle |
Beneficial effects of N-acetylcysteine in treatment resistant schizophrenia.
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pubmed:affiliation |
Department of Psychiatry, Gaziantep University Faculty of Medicine, Gaziantep, Turkey.
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pubmed:publicationType |
Journal Article
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