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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
8708
|
| pubmed:dateCreated |
1990-8-20
|
| pubmed:abstractText |
In a prospective, randomised, controlled trial to determine whether comprehensive lifestyle changes affect coronary atherosclerosis after 1 year, 28 patients were assigned to an experimental group (low-fat vegetarian diet, stopping smoking, stress management training, and moderate exercise) and 20 to a usual-care control group. 195 coronary artery lesions were analysed by quantitative coronary angiography. The average percentage diameter stenosis regressed from 40.0 (SD 16.9)% to 37.8 (16.5)% in the experimental group yet progressed from 42.7 (15.5)% to 46.1 (18.5)% in the control group. When only lesions greater than 50% stenosed were analysed, the average percentage diameter stenosis regressed from 61.1 (8.8)% to 55.8 (11.0)% in the experimental group and progressed from 61.7 (9.5)% to 64.4 (16.3)% in the control group. Overall, 82% of experimental-group patients had an average change towards regression. Comprehensive lifestyle changes may be able to bring about regression of even severe coronary atherosclerosis after only 1 year, without use of lipid-lowering drugs.
|
| pubmed:grant | |
| pubmed:commentsCorrections | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
AIM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jul
|
| pubmed:issn |
0140-6736
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
21
|
| pubmed:volume |
336
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
129-33
|
| pubmed:dateRevised |
2008-11-21
|
| pubmed:meshHeading |
pubmed-meshheading:1973470-Adult,
pubmed-meshheading:1973470-Aged,
pubmed-meshheading:1973470-Combined Modality Therapy,
pubmed-meshheading:1973470-Coronary Angiography,
pubmed-meshheading:1973470-Coronary Artery Disease,
pubmed-meshheading:1973470-Diet, Vegetarian,
pubmed-meshheading:1973470-Dietary Fats,
pubmed-meshheading:1973470-Exercise,
pubmed-meshheading:1973470-Female,
pubmed-meshheading:1973470-Humans,
pubmed-meshheading:1973470-Life Style,
pubmed-meshheading:1973470-Lipids,
pubmed-meshheading:1973470-Male,
pubmed-meshheading:1973470-Middle Aged,
pubmed-meshheading:1973470-Patient Compliance,
pubmed-meshheading:1973470-Prospective Studies,
pubmed-meshheading:1973470-Randomized Controlled Trials as Topic,
pubmed-meshheading:1973470-Sex Factors,
pubmed-meshheading:1973470-Smoking,
pubmed-meshheading:1973470-Social Support,
pubmed-meshheading:1973470-Stress, Physiological,
pubmed-meshheading:1973470-Time Factors
|
| pubmed:year |
1990
|
| pubmed:articleTitle |
Can lifestyle changes reverse coronary heart disease? The Lifestyle Heart Trial.
|
| pubmed:affiliation |
Pacific Presbyterian Medical Center, Sausalito, California.
|
| pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, U.S. Gov't, P.H.S.,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
|