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rdf:type |
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lifeskim:mentions |
umls-concept:C0017262,
umls-concept:C0021201,
umls-concept:C0026882,
umls-concept:C0035647,
umls-concept:C0185117,
umls-concept:C0242422,
umls-concept:C0376249,
umls-concept:C0392756,
umls-concept:C0813145,
umls-concept:C1418270,
umls-concept:C1705493,
umls-concept:C1709269,
umls-concept:C2911684
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pubmed:issue |
2
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pubmed:dateCreated |
2010-2-10
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pubmed:abstractText |
Among several aetiological factors, PARK2 mutations are the most common cause of Parkinson disease (PD) that result in degeneration of dopaminergic neurons in the substantia nigra.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1468-330X
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
81
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
166-70
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pubmed:meshHeading |
pubmed-meshheading:19734163-Catchment Area (Health),
pubmed-meshheading:19734163-DNA Primers,
pubmed-meshheading:19734163-Dopamine,
pubmed-meshheading:19734163-Exons,
pubmed-meshheading:19734163-Female,
pubmed-meshheading:19734163-Genetic Testing,
pubmed-meshheading:19734163-Humans,
pubmed-meshheading:19734163-India,
pubmed-meshheading:19734163-Male,
pubmed-meshheading:19734163-Middle Aged,
pubmed-meshheading:19734163-Nerve Degeneration,
pubmed-meshheading:19734163-Parkinsonian Disorders,
pubmed-meshheading:19734163-Point Mutation,
pubmed-meshheading:19734163-Polymerase Chain Reaction,
pubmed-meshheading:19734163-Prevalence,
pubmed-meshheading:19734163-Risk Factors,
pubmed-meshheading:19734163-Substantia Nigra,
pubmed-meshheading:19734163-Ubiquitin-Protein Ligases
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pubmed:year |
2010
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pubmed:articleTitle |
Genetic screening reveals high frequency of PARK2 mutations and reduced Parkin expression conferring risk for Parkinsonism in North West India.
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pubmed:affiliation |
Department of Neurology, Post Graduate Institute of Medical Education and Research, Sector-12 Chandigarh 160012, India. akshay1anand@rediffmail.com
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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