Linked Life Data

19732617

Source:http://linkedlifedata.com/resource/pubmed/id/19732617

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2009-9-7
pubmed:abstractText
There exists a link between the in utero metabolic environment and the development of the fetal nervous system. Prenatal neurosonography offers a unique, noninvasive tool in the detection of developmental brain malformations and the ability to monitor changes over time. This article explores the association of malformations of cerebral development reported in association with inborn errors of metabolism, and speculates on potential mechanisms by which such malformations arise. The detection of cerebral malformations prenatally should lead to a search for both genetic etiologies and inborn errors of metabolism in the fetus. Improving the changes of an early diagnosis provides for timely therapeutic interventions and it is hoped a brighter future for affected children and their families.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
1557-9840
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
36
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
621-38
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Primary disorders of metabolism and disturbed fetal brain development.
pubmed:affiliation
Section of Clinical Neurosciences, Department of Pediatrics and Child Health, Children's Hospital of Western Ontario, London Health Sciences Centre, University of Western Ontario, B-509, 800 Commissioners Road East, London, Ontario, N6C4G5, Canada.
pubmed:publicationType
Journal Article, Review