Linked Life Data

19731552

Source:http://linkedlifedata.com/resource/pubmed/id/19731552

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2009-9-7
pubmed:abstractText
In this chapter we review work on neurotrophic factors for midbrain dopaminergic neurons mainly from the past decade, with a focus on neurotrophins and fibroblast growth factors. We summarize data obtained from animal models of Parkinson's disease, review analyses of neurotrophin, neurotrophin receptor and FGF-2 knockout mice and put these into context with data obtained from patients with Parkinson's disease and from postmortem studies. We provide a brief overview on several other factors (EGF, TGF-alpha, IGF, CNTF, PDGF, interleukins) and their capacity to promote survival and protect lesioned DAergic neurons. TGF-betas are reviewed in a separate chapter (Roussa et al, this volume).
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0065-2598
pubmed:author
pubmed:issnType
Print
pubmed:volume
651
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
73-80
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Neurotrophic support of midbrain dopaminergic neurons.
pubmed:affiliation
Interdisciplinary Center for Neurosciences, Neuroanatomy, University of Heidelberg, Im Neuenheimer Feld 307 D-69120 Heidelberg, Germany. oliver.vonbohlen@arcor.de
pubmed:publicationType
Journal Article, Review