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pubmed:abstractText |
Group A Streptococcus pyogenes (GAS) exhibits a high degree of clinically relevant phenotypic diversity. Strains vary widely in terms of antibiotic resistance (AbR), clinical severity, and transmission rate. Currently, strain identification is achieved by emm typing (direct sequencing of the genomic segment coding for the antigenic portion of the M protein) or by multilocus genotyping methods. Phenotype analysis, including critical AbR typing, is generally achieved by much slower and more laborious direct culture-based methods.
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pubmed:affiliation |
Department of Respiratory Diseases Research, Naval Health Research Center, San Diego, California, United States of America. david.metzgar@med.navy.mil
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