rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
1
|
pubmed:dateCreated |
2009-12-4
|
pubmed:abstractText |
Enterocytes are exposed to antigens present in the intestinal lumen, like beta-glucans that are carbohydrate structures present not only in the cell wall of yeast and fungi but also in cereals. Beta-glucans are known for their immune modulating properties and we have earlier reported an increased immune response by enterocytes after addition of fecal water prepared from ileostomic contents obtained from participants consuming an oat beta-glucan diet versus a placebo diet. We hypothesized that our observation of immune stimulating effects by oat beta-glucan in enterocytes was mediated through the beta-glucan receptor dectin-1.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jan
|
pubmed:issn |
1473-5687
|
pubmed:author |
|
pubmed:issnType |
Electronic
|
pubmed:volume |
22
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
88-94
|
pubmed:meshHeading |
pubmed-meshheading:19730386-Body Water,
pubmed-meshheading:19730386-Caco-2 Cells,
pubmed-meshheading:19730386-Colon,
pubmed-meshheading:19730386-Enterocytes,
pubmed-meshheading:19730386-Feces,
pubmed-meshheading:19730386-Humans,
pubmed-meshheading:19730386-Ileum,
pubmed-meshheading:19730386-Interleukin-8,
pubmed-meshheading:19730386-Membrane Proteins,
pubmed-meshheading:19730386-NF-kappa B,
pubmed-meshheading:19730386-Nerve Tissue Proteins,
pubmed-meshheading:19730386-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:19730386-Zymosan,
pubmed-meshheading:19730386-beta-Glucans
|
pubmed:year |
2010
|
pubmed:articleTitle |
The absence of functional dectin-1 on enterocytes may serve to prevent intestinal damage.
|
pubmed:affiliation |
Departments of Human Biology, Nutrition and Toxicology Institute Maastricht, Maastricht University, NL-6200 MD Maastricht, The Netherlands.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|