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pubmed-article:19730237pubmed:abstractTextPersonalized medicine merges genetics, physiology, and patient outcome. Loss of physiologic complexity (heart rate [HR] variability) is a bedside biomarker for autonomic nervous system (ANS) dysfunction. We hypothesized that variability in ANS receptor proteins (genetics) and loss of complexity (physiology) are independently associated with mortality in critical illness.lld:pubmed
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pubmed-article:19730237pubmed:articleTitlePersonalized medicine: genetic variation and loss of physiologic complexity are associated with mortality in 644 trauma patients.lld:pubmed
pubmed-article:19730237pubmed:affiliationDivision of Trauma and Surgical Critical Care, Vanderbilt University, Nashville, Tennessee, USA. patrick.norris@vanderbilt.edulld:pubmed
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