Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2009-9-4
pubmed:abstractText
Antibiotic-resistant Streptococcus pneumoniae (Sp) are described around the world. The present national surveillance study report analyzes more than 6000 Sp strains, isolated from adults across France in 2001 and 2003, from blood cultures (3086 in 2001 and 3164 in 2003), cerebrospinal fluid (respectively, 238 and 240), or middle ear fluid (respectively, 110 and 100). The proportion of isolates with reduced susceptibility to penicillin fell significantly between 2001 and 2003 from 46.5% to 43.9%. The proportion of high-level resistant strains to penicillin minimal inhibitory concentrations (MIC > 1 mg/L), amoxicillin, and cefotaxime (MIC > 2 mg/L) slightly decreased but remained low: 10.6%, 1.2%, and 0.2% in 2003. Resistance to other antibiotics (erythromycin, cotrimoxazole, tetracycline, and chloramphenicol) also decreased. Decrease in prevalence of penicillin-resistant Sp varied according to specimen source. The proportion of penicillin nonsusceptible pneumococci decreased in blood cultures and middle ear fluids between 2001 and 2003 but increased in cerebrospinal fluid (43.4% and 46.5%, respectively). Serotypes covered by the heptavalent vaccine accounted for 42.4% of all isolates recovered in 2001 and 46.1% in 2003. Prevalence of antibiotic-resistant Sp decreased in 2003 in France.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
1931-8448
pubmed:author
pubmed-author:BourdonSandraS, pubmed-author:BrunMichelM, pubmed-author:CattierBlandineB, pubmed-author:ChanalCatherineC, pubmed-author:ChardonHubertH, pubmed-author:ChomaratMoniqueM, pubmed-author:CoignardBrunoB, pubmed-author:CroizéJacquesJ, pubmed-author:DemachyMarie-ClaudeMC, pubmed-author:DonnioPierre-YvesPY, pubmed-author:DupontPhilippeP, pubmed-author:FosseThierryT, pubmed-author:GravetAlainA, pubmed-author:GrignonBernadetteB, pubmed-author:GutmannLaurentL, pubmed-author:LauransGenevièveG, pubmed-author:MaugeinJeanneJ, pubmed-author:PéchinotAndréA, pubmed-author:PloyMarie-CécileMC, pubmed-author:PrèreMarie-FrançoiseMF, pubmed-author:Roussel-DelvallezMichelineM, pubmed-author:ThoreuxPierre-HenriPH, pubmed-author:VaronEmmanuelleE, pubmed-author:VergnaudMichelM, pubmed-author:Vernet-GarnierVéroniqueV, pubmed-author:WeberMichèleM
pubmed:issnType
Electronic
pubmed:volume
15
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
201-4
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Serotype distribution and antibiotic resistance of Streptococcus pneumoniae strains isolated from adults in France: evolution between 2001 and 2003.
pubmed:affiliation
University Hospital Center (CHU) Lille-Regional Pneumococcal Observatories (ORP) Nord-Pas-de-Calais, Lille, France.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't