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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8703
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pubmed:dateCreated |
1990-7-18
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pubmed:abstractText |
In a prospective study of street-recruited intravenous drug users (IVDUs) in Miami, Florida, USA, 107 (46.5%) of 230 IVDUs were infected with HIV-1. Of these HIV-1 seropositive individuals, 23 were also infected with human T-lymphotropic virus type I or II (HTLV-I/II). To test the hypothesis that HTLV-I/II infection has an effect on the survival of HIV-1 seropositive IVDUs, various baseline clinical and laboratory HIV-1 related indices in HTLV-I/II positive and negative groups were compared. Life table analysis and Cox's proportional hazards model were used to estimate the potential effect of HTLV-I/II infection on the survival patterns of people infected with HIV-1. IVDUs infected with both viruses were three times more likely to die from AIDS during follow-up than were those infected with HIV-1 only. This finding suggests that HTLV-I/II seropositivity may adversely affect the clinical outcome of HIV-1 seropositive patients.
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pubmed:grant | |
pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
|
pubmed:issn |
0140-6736
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
16
|
pubmed:volume |
335
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
1439-41
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:1972217-Acquired Immunodeficiency Syndrome,
pubmed-meshheading:1972217-Actuarial Analysis,
pubmed-meshheading:1972217-Adult,
pubmed-meshheading:1972217-Antigens, CD4,
pubmed-meshheading:1972217-Evaluation Studies as Topic,
pubmed-meshheading:1972217-Female,
pubmed-meshheading:1972217-Follow-Up Studies,
pubmed-meshheading:1972217-HTLV-I Antibodies,
pubmed-meshheading:1972217-HTLV-I Infections,
pubmed-meshheading:1972217-HTLV-II Antibodies,
pubmed-meshheading:1972217-HTLV-II Infections,
pubmed-meshheading:1972217-Humans,
pubmed-meshheading:1972217-Male,
pubmed-meshheading:1972217-Prospective Studies,
pubmed-meshheading:1972217-Substance Abuse, Intravenous
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pubmed:year |
1990
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pubmed:articleTitle |
HTLV-I/II seropositivity and death from AIDS among HIV-1 seropositive intravenous drug users.
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pubmed:affiliation |
University of Miami School of Medicine, Florida.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.
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