Linked Life Data

19719182

Source:http://linkedlifedata.com/resource/pubmed/id/19719182

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
15
pubmed:dateCreated
2009-9-1
pubmed:abstractText
A novel and efficient method has been developed for the synthesis of tetrahydro-2,4-dioxo-1H-benzo[b][1,5]diazepine-3-yl-2-methylpropanamide derivatives using an aromatic diamine, Meldrum's acid, and an isocyanide in CH(2)Cl(2) at ambient temperature in high yields without using any catalyst or activation. The procedure provides an alternative method for the synthesis of benzo[b][1,5]diazepine derivatives. These compounds have closely related ring systems such as triflubazam, clobazam, and 1,5-benzodiazepines, which have a broad spectrum of biological activities.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
1523-7052
pubmed:author
pubmed:issnType
Electronic
pubmed:day
6
pubmed:volume
11
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
3342-5
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
A novel one-pot three-(in situ five-)component condensation reaction: an unexpected approach for the synthesis of tetrahydro-2,4-dioxo-1H-benzo[b][1,5]diazepine-3-yl-2-methylpropanamide derivatives.
pubmed:affiliation
Department of Chemistry, Shahid Beheshti University, P.O. Box 19396-4716, Tehran, Iran. a-shaabani@cc.sbu.ac.ir
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't