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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
8
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pubmed:dateCreated |
2009-8-31
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pubmed:abstractText |
In genetic studies of rare complex diseases it is common to ascertain familial data from population based registries through all incident cases diagnosed during a pre-defined enrollment period. Such an ascertainment procedure is typically taken into account in the statistical analysis of the familial data by constructing either a retrospective or prospective likelihood expression, which conditions on the ascertainment event. Both of these approaches lead to a substantial loss of valuable data.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/19718441-10686502,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19718441-10712222,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19718441-11254454,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19718441-11719900,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19718441-11984867,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19718441-12182119,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19718441-12508253,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19718441-1348711,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19718441-15192279,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19718441-15292346,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19718441-1541383,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19718441-15456105,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19718441-17323369,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19718441-2569104,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19718441-8013897,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19718441-8557177,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19718441-8557178,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19718441-8651310,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19718441-9730037
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:issn |
1932-6203
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
4
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
e6836
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pubmed:meshHeading |
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pubmed:year |
2009
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pubmed:articleTitle |
Full likelihood analysis of genetic risk with variable age at onset disease--combining population-based registry data and demographic information.
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pubmed:affiliation |
Department of Public Health, University of Helsinki, Helsinki, Finland. janne.pitkaniemi@helsinki.fi
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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