Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
2009-8-31
pubmed:abstractText
This paper focuses on invasive therapeutic procedures, defined as procedures requiring the introduction of hands, instruments, or devices into the body via incisions or punctures of the skin or mucous membranes performed with the intent of changing the natural history of a human disease or condition for the better. Ethical and methodological concerns have been expressed about studies designed to evaluate the effects of invasive therapeutic procedures. Can such studies meet the same standards demanded of those, for example, evaluating pharmaceutical agents? This paper describes a research project aimed at examining the interplay and sometimes apparent conflict between ethical standards for human research and standards for methodological rigor in trials of invasive procedures. The paper discusses how the authors plan to develop a set of consensus standards that, if met, would result in substantial and much-needed improvements in the methodological and ethical quality of such trials.
pubmed:grant
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/19717699-10999914, http://linkedlifedata.com/resource/pubmed/commentcorrection/19717699-11304106, http://linkedlifedata.com/resource/pubmed/commentcorrection/19717699-11403808, http://linkedlifedata.com/resource/pubmed/commentcorrection/19717699-14941297, http://linkedlifedata.com/resource/pubmed/commentcorrection/19717699-15356289, http://linkedlifedata.com/resource/pubmed/commentcorrection/19717699-15470212, http://linkedlifedata.com/resource/pubmed/commentcorrection/19717699-15746454, http://linkedlifedata.com/resource/pubmed/commentcorrection/19717699-16186516, http://linkedlifedata.com/resource/pubmed/commentcorrection/19717699-16304982, http://linkedlifedata.com/resource/pubmed/commentcorrection/19717699-17119140, http://linkedlifedata.com/resource/pubmed/commentcorrection/19717699-17224571, http://linkedlifedata.com/resource/pubmed/commentcorrection/19717699-17943745, http://linkedlifedata.com/resource/pubmed/commentcorrection/19717699-18304582, http://linkedlifedata.com/resource/pubmed/commentcorrection/19717699-1852179, http://linkedlifedata.com/resource/pubmed/commentcorrection/19717699-18827106, http://linkedlifedata.com/resource/pubmed/commentcorrection/19717699-19228627, http://linkedlifedata.com/resource/pubmed/commentcorrection/19717699-2865674, http://linkedlifedata.com/resource/pubmed/commentcorrection/19717699-3279313, http://linkedlifedata.com/resource/pubmed/commentcorrection/19717699-355881, http://linkedlifedata.com/resource/pubmed/commentcorrection/19717699-3600702, http://linkedlifedata.com/resource/pubmed/commentcorrection/19717699-7743790, http://linkedlifedata.com/resource/pubmed/commentcorrection/19717699-8610329, http://linkedlifedata.com/resource/pubmed/commentcorrection/19717699-9811916
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
E
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
1473-4257
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
35
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
579-83
pubmed:dateRevised
2011-9-26
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Ethics and methods in surgical trials.
pubmed:affiliation
Department of Surgery, The Methodist Hospital, Houston, Texas, USA. cashton@tmhs.org
pubmed:publicationType
Journal Article