|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
6
|
|
pubmed:dateCreated |
2009-10-30
|
|
pubmed:abstractText |
Airway mucus hypersecretion is an important problem in chronic respiratory diseases including bronchial asthma. Chlamydophila pneumoniae is recently confirmed to be a pathogen in bronchial asthma, but the relationship between C. pneumoniae and mucus hypersecretion is uncertain. In this study, we examined whether C. pneumoniae induces MUC5AC mucin in airway epithelial cells. We also examined the effects of macrolide and ketolide antibiotics on the C. pneumoniae-induced mucus production.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Anti-Bacterial Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Azithromycin,
http://linkedlifedata.com/resource/pubmed/chemical/Clarithromycin,
http://linkedlifedata.com/resource/pubmed/chemical/Extracellular Signal-Regulated MAP...,
http://linkedlifedata.com/resource/pubmed/chemical/Ketolides,
http://linkedlifedata.com/resource/pubmed/chemical/Muc5ac protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Mucin 5AC,
http://linkedlifedata.com/resource/pubmed/chemical/NF-kappa B,
http://linkedlifedata.com/resource/pubmed/chemical/NF-kappa B p50 Subunit,
http://linkedlifedata.com/resource/pubmed/chemical/Transcription Factor RelA,
http://linkedlifedata.com/resource/pubmed/chemical/telithromycin
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Dec
|
|
pubmed:issn |
1522-9629
|
|
pubmed:author |
pubmed-author:IzumikawaKoichiK,
pubmed-author:KakeyaHiroshiH,
pubmed-author:KamihiraShimeruS,
pubmed-author:KohnoShigeruS,
pubmed-author:MiyashitaNaoyukiN,
pubmed-author:MorinagaYoshitomoY,
pubmed-author:MukaeHiroshiH,
pubmed-author:SekiMasafumiM,
pubmed-author:YamadaYasuakiY,
pubmed-author:YamamotoYoshihiroY,
pubmed-author:YanagiharaKatsunoriK
|
|
pubmed:issnType |
Electronic
|
|
pubmed:volume |
22
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
580-6
|
|
pubmed:meshHeading |
pubmed-meshheading:19716898-Animals,
pubmed-meshheading:19716898-Anti-Bacterial Agents,
pubmed-meshheading:19716898-Azithromycin,
pubmed-meshheading:19716898-Blotting, Western,
pubmed-meshheading:19716898-Cells, Cultured,
pubmed-meshheading:19716898-Chlamydophila Infections,
pubmed-meshheading:19716898-Chlamydophila pneumoniae,
pubmed-meshheading:19716898-Clarithromycin,
pubmed-meshheading:19716898-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:19716898-Epithelial Cells,
pubmed-meshheading:19716898-Extracellular Signal-Regulated MAP Kinases,
pubmed-meshheading:19716898-Gene Expression,
pubmed-meshheading:19716898-Ketolides,
pubmed-meshheading:19716898-Mice,
pubmed-meshheading:19716898-Mucin 5AC,
pubmed-meshheading:19716898-NF-kappa B,
pubmed-meshheading:19716898-NF-kappa B p50 Subunit,
pubmed-meshheading:19716898-Respiratory Mucosa,
pubmed-meshheading:19716898-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:19716898-Transcription Factor RelA
|
|
pubmed:year |
2009
|
|
pubmed:articleTitle |
Azithromycin, clarithromycin and telithromycin inhibit MUC5AC induction by Chlamydophila pneumoniae in airway epithelial cells.
|
|
pubmed:affiliation |
Department of Laboratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan.
|
|
pubmed:publicationType |
Journal Article
|
