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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:dateCreated |
1990-7-5
|
| pubmed:abstractText |
An open prospective randomized trial was conducted in three Italian ear, nose and throat (ENT) surgery departments on 120 patients aged 10 to 84 years, to compare a single pre-operative dose vs. three peri-operative doses of ceftazidime in surgical prophylaxis. Sixty patients in group I received 1 g ceftazidime intramuscularly (im) or intravenously (iv) 1 h before surgery, and 60 in group II received three 1 g doses of ceftazidime, im or iv, 1 h before, and 6 and 12 h after surgery. Post-operative infections were observed in six group I patients (10.1%) and seven group II patients (11.6%). All infections arose in patients who had undergone 'moderate-risk' (6.7%) or 'high-risk' surgery (30.5%). We conclude that a single pre-operative 1 g dose of ceftazidime is as efficacious as multiple peri-operative doses in the prophylaxis of infectious complications following this type of surgery.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Apr
|
| pubmed:issn |
0195-6701
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
15 Suppl A
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
81-5
|
| pubmed:dateRevised |
2007-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:1971651-Adolescent,
pubmed-meshheading:1971651-Adult,
pubmed-meshheading:1971651-Aged,
pubmed-meshheading:1971651-Aged, 80 and over,
pubmed-meshheading:1971651-Ceftazidime,
pubmed-meshheading:1971651-Cross Infection,
pubmed-meshheading:1971651-Female,
pubmed-meshheading:1971651-Humans,
pubmed-meshheading:1971651-Infection,
pubmed-meshheading:1971651-Infection Control,
pubmed-meshheading:1971651-Infusions, Intravenous,
pubmed-meshheading:1971651-Injections, Intramuscular,
pubmed-meshheading:1971651-Italy,
pubmed-meshheading:1971651-Male,
pubmed-meshheading:1971651-Middle Aged,
pubmed-meshheading:1971651-Otorhinolaryngologic Diseases,
pubmed-meshheading:1971651-Postoperative Complications,
pubmed-meshheading:1971651-Premedication,
pubmed-meshheading:1971651-Prospective Studies,
pubmed-meshheading:1971651-Randomized Controlled Trials as Topic
|
| pubmed:year |
1990
|
| pubmed:articleTitle |
Antibiotic prophylaxis in ear, nose and throat surgery: a comparison of a single preoperative dose with three peri-operative doses of ceftazidime.
|
| pubmed:affiliation |
ENT Department, Hospital of Viterbo, Italy.
|
| pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Randomized Controlled Trial
|