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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2009-9-16
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pubmed:abstractText |
The Golgi apparatus in mammals appears as a ribbon made up of interconnected stacks of flattened cisternae that is positioned close to the centrosome in a microtubule-dependent manner. How this organisation is achieved and retained is not well understood. GMAP210 is a long coiled-coil cis-Golgi associated protein that plays a role in maintaining Golgi ribbon integrity and position and contributes to the formation of the primary cilium. An amphipathic alpha-helix able to bind liposomes in vitro has been recently identified at the first 38 amino acids of the protein (amphipathic lipid-packing sensor motif), and an ARF1-binding domain (Grip-related Arf-binding domain) was found at the C-terminus. To which type of membranes these two GMAP210 regions bind in vivo and how this contributes to GMAP210 localisation and function remains to be investigated.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/19715559-10189370,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19715559-11463340,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19715559-12383348,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19715559-12517705,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19715559-14745494,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19715559-15294158,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19715559-15504911,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19715559-15944734,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19715559-16042562,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19715559-16251359,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19715559-16316994,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19715559-16489344,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19715559-16775004,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19715559-16882688,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19715559-16904228,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19715559-16938456,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19715559-17035995,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19715559-17084359,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19715559-17220896,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19715559-17253781,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19715559-17314401,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19715559-17352745,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19715559-18195007,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19715559-18434598,
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http://linkedlifedata.com/resource/pubmed/commentcorrection/19715559-18693248,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19715559-19001129,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19715559-19106097,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19715559-19112494,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19715559-19158377,
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http://linkedlifedata.com/resource/pubmed/commentcorrection/19715559-9925741
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Autoantigens,
http://linkedlifedata.com/resource/pubmed/chemical/GOLGA4 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Mutant Chimeric Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/N-Acetyllactosamine Synthase,
http://linkedlifedata.com/resource/pubmed/chemical/Nuclear Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Small Interfering,
http://linkedlifedata.com/resource/pubmed/chemical/Recombinant Fusion Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/TRIP11 protein, human
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pubmed:status |
MEDLINE
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pubmed:issn |
1741-7007
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
7
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
56
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:19715559-Amino Acid Sequence,
pubmed-meshheading:19715559-Autoantigens,
pubmed-meshheading:19715559-Cell Line,
pubmed-meshheading:19715559-Centrosome,
pubmed-meshheading:19715559-Cytosol,
pubmed-meshheading:19715559-Endoplasmic Reticulum,
pubmed-meshheading:19715559-Gene Expression,
pubmed-meshheading:19715559-Golgi Apparatus,
pubmed-meshheading:19715559-Humans,
pubmed-meshheading:19715559-Membrane Proteins,
pubmed-meshheading:19715559-Microscopy, Fluorescence,
pubmed-meshheading:19715559-Microscopy, Video,
pubmed-meshheading:19715559-Models, Biological,
pubmed-meshheading:19715559-Molecular Sequence Data,
pubmed-meshheading:19715559-Mutant Chimeric Proteins,
pubmed-meshheading:19715559-N-Acetyllactosamine Synthase,
pubmed-meshheading:19715559-Nuclear Proteins,
pubmed-meshheading:19715559-Protein Biosynthesis,
pubmed-meshheading:19715559-Protein Interaction Domains and Motifs,
pubmed-meshheading:19715559-Protein Transport,
pubmed-meshheading:19715559-RNA, Small Interfering,
pubmed-meshheading:19715559-Recombinant Fusion Proteins,
pubmed-meshheading:19715559-Retinal Pigment Epithelium,
pubmed-meshheading:19715559-Secretory Pathway,
pubmed-meshheading:19715559-Transfection
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pubmed:year |
2009
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pubmed:articleTitle |
Golgi localisation of GMAP210 requires two distinct cis-membrane binding mechanisms.
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pubmed:affiliation |
CABIMER-CSIC, Seville, Spain. jesus.cardenas@cabimer.es
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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