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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
11
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pubmed:dateCreated |
2010-1-29
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pubmed:abstractText |
The purpose of the current study was to assess the effect of newly synthesized Curcumin analogs on COX-2 protein by molecular docking studies and by assessments of the effect of one such analog (CDF) on nuclear factor NF-kappaB and PGE(2). In addition, we have determined the pharmacokinetics and tissue distribution of CDF in mice compared to Curcumin.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1573-904X
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
26
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2438-45
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pubmed:meshHeading |
pubmed-meshheading:19714451-Animals,
pubmed-meshheading:19714451-Antineoplastic Agents,
pubmed-meshheading:19714451-Cell Line, Tumor,
pubmed-meshheading:19714451-Chromatography, High Pressure Liquid,
pubmed-meshheading:19714451-Curcumin,
pubmed-meshheading:19714451-Cyclooxygenase 2,
pubmed-meshheading:19714451-Cyclooxygenase 2 Inhibitors,
pubmed-meshheading:19714451-Female,
pubmed-meshheading:19714451-Humans,
pubmed-meshheading:19714451-Mice,
pubmed-meshheading:19714451-Mice, SCID,
pubmed-meshheading:19714451-Models, Molecular,
pubmed-meshheading:19714451-Pancreatic Neoplasms,
pubmed-meshheading:19714451-Tissue Distribution
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pubmed:year |
2009
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pubmed:articleTitle |
Fluorocurcumins as cyclooxygenase-2 inhibitor: molecular docking, pharmacokinetics and tissue distribution in mice.
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pubmed:affiliation |
D.Y.Patil Institute of Pharmaceutical Sciences, Pune, 411018, India.
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pubmed:publicationType |
Journal Article
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