Hormonal therapy (HT) when added to radiation therapy (RT) for treating unfavorable-risk prostate cancer leads to an increase in survival except possibly in men with moderate to severe comorbidity. However, it is unknown which comorbid conditions eliminate this survival benefit.
Harvard Radiation Oncology Program, Brigham & Women's Hospital-Dana-Farber Cancer Institute, 75 Francis St, ASB1 L2, Boston, MA 02115, USA. ananda@partners.org