Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2010-6-11
pubmed:abstractText
The diagnosis of sideroblastic anemia is based on bone marrow aspiration, and the detection of ring sideroblasts (RS) in iron staining. The finding of laboratory parameters to approach this diagnosis still remains a great challenge. In this study, we analyzed the value of a specific erythrogram pattern from peripheral blood, produced by the ADVIA120 cell counter, to predict sideroblastic changes in the bone marrow. In a two step-design study, we first showed that 32/38 consecutive patients reporting > or =15% RS had such a pattern in the erythrogram. In the second step, we prospectively identified over a period of 32 months 21 patients with this typical erythrogram; 20/21 had > or =15% RS in the bone marrow. Hence, by this validation, we confirm that the erythrogram is highly predictive of RS in the bone marrow. The interpretation of the erythrogram should become daily practice in hematology to improve the efficacy to detect sideroblastic changes.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/19706066-11737617, http://linkedlifedata.com/resource/pubmed/commentcorrection/19706066-11934218, http://linkedlifedata.com/resource/pubmed/commentcorrection/19706066-12068795, http://linkedlifedata.com/resource/pubmed/commentcorrection/19706066-1339929, http://linkedlifedata.com/resource/pubmed/commentcorrection/19706066-15590394, http://linkedlifedata.com/resource/pubmed/commentcorrection/19706066-15647011, http://linkedlifedata.com/resource/pubmed/commentcorrection/19706066-16568320, http://linkedlifedata.com/resource/pubmed/commentcorrection/19706066-1739797, http://linkedlifedata.com/resource/pubmed/commentcorrection/19706066-2706901, http://linkedlifedata.com/resource/pubmed/commentcorrection/19706066-3121463, http://linkedlifedata.com/resource/pubmed/commentcorrection/19706066-8212996, http://linkedlifedata.com/resource/pubmed/commentcorrection/19706066-8408707, http://linkedlifedata.com/resource/pubmed/commentcorrection/19706066-9211366
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
1751-553X
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
32
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
329-35
pubmed:dateRevised
2010-9-27
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Sideroblastic changes of the bone marrow can be predicted by the erythrogram of peripheral blood.
pubmed:affiliation
Hematology, University Hospital of Basel, Basel, Switzerland. ARovo@uhbs.ch
pubmed:publicationType
Journal Article