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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2009-8-25
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pubmed:abstractText |
The Epstein-Barr virus (EBV) protease (PR), coded by the BVRF2 gene, is essential for the maturation of the viral capsid and viral DNA packaging during the late stage of the EBV lytic cycle. Like the other herpesvirus serine PRs, EBV PR could be a target for the inhibition of EBV replication. To date, no data have been reported on the inhibition of EBV PR messenger RNA (mRNA) by small interfering RNA (siRNA).
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1359-6535
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pubmed:author |
pubmed-author:BasArianeA,
pubmed-author:BoyerVéroniqueV,
pubmed-author:BuissonMarlyseM,
pubmed-author:BurmeisterWim PWP,
pubmed-author:CranceJean-MarcJM,
pubmed-author:GermiRaphaëleR,
pubmed-author:GrossiLaurenceL,
pubmed-author:LarratSylvieS,
pubmed-author:MorandPatriceP,
pubmed-author:NicodSandrineS,
pubmed-author:SeigneurinJean-MarieJM,
pubmed-author:VigneSolenneS
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pubmed:issnType |
Print
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pubmed:volume |
14
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
655-62
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pubmed:meshHeading |
pubmed-meshheading:19704168-Cell Line,
pubmed-meshheading:19704168-Gene Expression Regulation, Viral,
pubmed-meshheading:19704168-Herpesvirus 4, Human,
pubmed-meshheading:19704168-Humans,
pubmed-meshheading:19704168-Peptide Hydrolases,
pubmed-meshheading:19704168-RNA, Messenger,
pubmed-meshheading:19704168-RNA, Small Interfering,
pubmed-meshheading:19704168-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:19704168-Viral Proteins,
pubmed-meshheading:19704168-Virus Replication
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pubmed:year |
2009
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pubmed:articleTitle |
Inhibition of Epstein-Barr virus replication by small interfering RNA targeting the Epstein-Barr virus protease gene.
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pubmed:affiliation |
UMI 3265, UJF-EMBL-CNRS, Unit of Virus Host Cell Interactions, Grenoble, France.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Evaluation Studies
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