| pubmed-article:19704122 | rdf:type | pubmed:Citation | lld:pubmed |
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| pubmed-article:19704122 | lifeskim:mentions | umls-concept:C0014898 | lld:lifeskim |
| pubmed-article:19704122 | lifeskim:mentions | umls-concept:C0028621 | lld:lifeskim |
| pubmed-article:19704122 | lifeskim:mentions | umls-concept:C0441655 | lld:lifeskim |
| pubmed-article:19704122 | lifeskim:mentions | umls-concept:C0036315 | lld:lifeskim |
| pubmed-article:19704122 | lifeskim:mentions | umls-concept:C0162388 | lld:lifeskim |
| pubmed-article:19704122 | lifeskim:mentions | umls-concept:C1533691 | lld:lifeskim |
| pubmed-article:19704122 | lifeskim:mentions | umls-concept:C1516048 | lld:lifeskim |
| pubmed-article:19704122 | lifeskim:mentions | umls-concept:C0439596 | lld:lifeskim |
| pubmed-article:19704122 | lifeskim:mentions | umls-concept:C0260127 | lld:lifeskim |
| pubmed-article:19704122 | pubmed:issue | 12 | lld:pubmed |
| pubmed-article:19704122 | pubmed:dateCreated | 2009-11-17 | lld:pubmed |
| pubmed-article:19704122 | pubmed:abstractText | 9-(S)-[3-Hydroxy-2-(phosphonomethoxy)propyl]adenine [(S)-HPMPA] has been reported to have antischistosomal activity. Ether lipid esters of (S)-HPMPA and cidofovir (CDV) have greatly increased activities in antiviral assays and in lethal animal models of poxvirus diseases. To see if ether lipid esters of CDV and (S)-HPMPA enhance antischistosomal activity, we tested their alkoxyalkyl esters using Schistosoma mansoni worm killing in vitro. Hexadecyloxypropyl (HDP)-cyclic-(S)-HPMPA and HDP-cyclic-CDV exhibited significant in vitro antischistosomal activities and may offer promise alone or in combination with praziquantel. | lld:pubmed |
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| pubmed-article:19704122 | pubmed:language | eng | lld:pubmed |
| pubmed-article:19704122 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19704122 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:19704122 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:19704122 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:19704122 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:19704122 | pubmed:issn | 1098-6596 | lld:pubmed |
| pubmed-article:19704122 | pubmed:author | pubmed-author:HostetlerKarl... | lld:pubmed |
| pubmed-article:19704122 | pubmed:author | pubmed-author:BeadleJames... | lld:pubmed |
| pubmed-article:19704122 | pubmed:author | pubmed-author:WilliamSamiaS | lld:pubmed |
| pubmed-article:19704122 | pubmed:author | pubmed-author:BotrosSanaa... | lld:pubmed |
| pubmed-article:19704122 | pubmed:author | pubmed-author:ValiaevaNadej... | lld:pubmed |
| pubmed-article:19704122 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:19704122 | pubmed:volume | 53 | lld:pubmed |
| pubmed-article:19704122 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:19704122 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:19704122 | pubmed:pagination | 5284-7 | lld:pubmed |
| pubmed-article:19704122 | pubmed:dateRevised | 2011-2-16 | lld:pubmed |
| pubmed-article:19704122 | pubmed:meshHeading | pubmed-meshheading:19704122... | lld:pubmed |
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| pubmed-article:19704122 | pubmed:meshHeading | pubmed-meshheading:19704122... | lld:pubmed |
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| pubmed-article:19704122 | pubmed:meshHeading | pubmed-meshheading:19704122... | lld:pubmed |
| pubmed-article:19704122 | pubmed:year | 2009 | lld:pubmed |
| pubmed-article:19704122 | pubmed:articleTitle | Antischistosomal activity of hexadecyloxypropyl cyclic 9-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]adenine and other alkoxyalkyl esters of acyclic nucleoside phosphonates assessed by schistosome worm killing in vitro. | lld:pubmed |
| pubmed-article:19704122 | pubmed:affiliation | Department of Pharmacology, Theodor Bilharz Research Institute, Warrak el-Hadar, Imbaba, Giza, Egypt. | lld:pubmed |
| pubmed-article:19704122 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:19704122 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| pubmed-article:19704122 | pubmed:publicationType | Research Support, N.I.H., Extramural | lld:pubmed |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | pubmed-article:19704122 | lld:chembl |
