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rdf:type |
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|
lifeskim:mentions |
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pubmed:issue |
27
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pubmed:dateCreated |
2009-10-2
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pubmed:abstractText |
The addition of monoclonal antibodies to chemotherapy has significantly improved treatment of chronic lymphocytic leukemia (CLL). Based on excellent results with the chemotherapy-only regimen fludarabine, cyclophosphamide, and mitoxantrone (FCM), we built a new chemoimmunotherapy combination--rituximab plus FCM (R-FCM). We report a phase II clinical trial consisting of an initial treatment with R-FCM followed by rituximab maintenance.
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pubmed:language |
eng
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pubmed:journal |
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|
pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1527-7755
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pubmed:author |
pubmed-author:AbellaEugeniaE,
pubmed-author:AbrisquetaPauP,
pubmed-author:BoschFrancescF,
pubmed-author:CarbonellFélixF,
pubmed-author:DelgadoJulioJ,
pubmed-author:EscodaLourdesL,
pubmed-author:EstanyCristinaC,
pubmed-author:FerraChristelleC,
pubmed-author:FerrerSecundinoS,
pubmed-author:García MarcoJosé AntonioJA,
pubmed-author:González DiazMarcosM,
pubmed-author:González-BarcaEvaE,
pubmed-author:GonzálezYolandaY,
pubmed-author:JarqueIsidroI,
pubmed-author:MontserratEmiliE,
pubmed-author:MonzóEncarnaciónE,
pubmed-author:MuntañolaAnaA,
pubmed-author:SalameroOlgaO,
pubmed-author:TerolMaría JoséMJ,
pubmed-author:VillamorNeusN
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pubmed:issnType |
Electronic
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pubmed:day |
20
|
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pubmed:volume |
27
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
4578-84
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:19704063-Adult,
pubmed-meshheading:19704063-Aged,
pubmed-meshheading:19704063-Antibodies, Monoclonal,
pubmed-meshheading:19704063-Antibodies, Monoclonal, Murine-Derived,
pubmed-meshheading:19704063-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:19704063-Cyclophosphamide,
pubmed-meshheading:19704063-Female,
pubmed-meshheading:19704063-Humans,
pubmed-meshheading:19704063-Leukemia, Lymphocytic, Chronic, B-Cell,
pubmed-meshheading:19704063-Male,
pubmed-meshheading:19704063-Middle Aged,
pubmed-meshheading:19704063-Mitoxantrone,
pubmed-meshheading:19704063-Vidarabine
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pubmed:year |
2009
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pubmed:articleTitle |
Rituximab, fludarabine, cyclophosphamide, and mitoxantrone: a new, highly active chemoimmunotherapy regimen for chronic lymphocytic leukemia.
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pubmed:affiliation |
Department of Hematology, Hospital Clínic, Villarroel 170, 08036 Barcelona, Spain. fbosch@clinic.ub.es
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't,
Clinical Trial, Phase II
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