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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1990-5-25
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pubmed:abstractText |
Primary allo-stimulation induces substantial and differentiated modifications in the development of cytoplasmic organelles of peripheral T-lymphocyte subsets. The present computer-assisted image analysis provides evidence that the CD4+ subset undergoes significant increase in organelle density after stimulation, while the CD8+ subset exhibits a post-stimulation organelle development proportional to the cell size. Each immunological subset contains two distinct patterns of cytoplasmic organization, here defined as type I (containing a few cytoplasmic organelles) and type II (with well-developed synthesis and storage organelles). On the basis of these findings cytologic parameters could be ascribed to a heterogeneous proliferation of functionally distinct T-cell clones in CD4+ and CD8+ subsets.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Mar
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pubmed:issn |
0902-4441
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
44
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
179-85
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1970307-CD4-Positive T-Lymphocytes,
pubmed-meshheading:1970307-Cell Division,
pubmed-meshheading:1970307-Cells, Cultured,
pubmed-meshheading:1970307-Histocompatibility Antigens Class II,
pubmed-meshheading:1970307-Humans,
pubmed-meshheading:1970307-Image Processing, Computer-Assisted,
pubmed-meshheading:1970307-Lymphocyte Activation,
pubmed-meshheading:1970307-Microscopy, Electron,
pubmed-meshheading:1970307-T-Lymphocytes, Cytotoxic,
pubmed-meshheading:1970307-T-Lymphocytes, Regulatory
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pubmed:year |
1990
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pubmed:articleTitle |
Allo-activated CD4+ and CD8+ lymphocyte subsets: new ultrastructural findings based on computer-assisted image analysis.
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pubmed:affiliation |
Institute of Human Anatomy and Histology, University of Verona, Italy.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|