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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2009-11-25
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pubmed:abstractText |
CD14 is a key molecule in innate immunity that mediates cell activation and signaling in response to endotoxin and other bacterial wall-derived components. CD14 protein exists in soluble (sCD14) and membrane-bound forms. The correlates of sCD14 in persons undergoing long-term hemodialysis (HD) therapy are not known. We hypothesized that increased sCD14 levels in HD patients are associated with proinflammatory cytokine activation and increased mortality.
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pubmed:grant |
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1523-6838
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
54
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1062-71
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pubmed:dateRevised |
2011-9-22
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pubmed:meshHeading |
pubmed-meshheading:19699018-Adult,
pubmed-meshheading:19699018-Aged,
pubmed-meshheading:19699018-Antigens, CD14,
pubmed-meshheading:19699018-Biological Markers,
pubmed-meshheading:19699018-C-Reactive Protein,
pubmed-meshheading:19699018-Cohort Studies,
pubmed-meshheading:19699018-Female,
pubmed-meshheading:19699018-Humans,
pubmed-meshheading:19699018-Inflammation,
pubmed-meshheading:19699018-Interleukin-6,
pubmed-meshheading:19699018-Kaplan-Meier Estimate,
pubmed-meshheading:19699018-Kidney Failure, Chronic,
pubmed-meshheading:19699018-Male,
pubmed-meshheading:19699018-Middle Aged,
pubmed-meshheading:19699018-Predictive Value of Tests,
pubmed-meshheading:19699018-Proportional Hazards Models,
pubmed-meshheading:19699018-Protein-Energy Malnutrition,
pubmed-meshheading:19699018-Renal Dialysis,
pubmed-meshheading:19699018-Survival Rate,
pubmed-meshheading:19699018-Tumor Necrosis Factor-alpha,
pubmed-meshheading:19699018-United States
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pubmed:year |
2009
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pubmed:articleTitle |
Association of soluble endotoxin receptor CD14 and mortality among patients undergoing hemodialysis.
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pubmed:affiliation |
George Washington University School of Medicine, North Washington, DC, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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