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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2009-9-7
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pubmed:abstractText |
Statistical power calculations are a critical part of any study design for gene mapping. Most calculations assume that the locus of interest is biallelic. However, there are common situations in human genetics such as X-linked loci in males where the locus is haploid. The purpose of this work is to mathematically derive the biometric model for haploid loci, and to compute power for QTL mapping when the loci are haploid.
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pubmed:grant |
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:issn |
1471-2105
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
261
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pubmed:meshHeading |
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pubmed:year |
2009
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pubmed:articleTitle |
Computing power of quantitative trait locus association mapping for haploid loci.
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pubmed:affiliation |
Department of Genetics, Rutgers University, 145 Bevier Road, Piscataway, NJ 08854, USA. gordon@biology.rutgers.edu
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
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