Linked Life Data

19695918

Source:http://linkedlifedata.com/resource/pubmed/id/19695918

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2010-4-26
pubmed:abstractText
Good's syndrome (GS) is an immunodeficiency characterized by thymoma, hypogammaglobulinemia, and impaired T-cell function. The clinical manifestations of GS include recurrent or chronic infections from common or opportunistic pathogens. Encephalitis is a rare event, with only anecdotal reports of cytomegalovirus infection. Herein we report the case of a 79-year-old woman with GS who developed subacute motor deficits and cognitive changes. Magnetic resonance imaging (MRI) of the brain disclosed white- and gray-matter lesions, mostly in the right frontal and parietal areas. Polyoma virus JC, the agent of progressive multifocal encephalopathy (PML), was identified in cerebrospinal fluid samples and brain biopsy specimens. After diagnosis, the disease had a rapid fatal course. The present case represents the first reported association between GS and PML.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
1878-3511
pubmed:author
pubmed:copyrightInfo
Copyright 2009 International Society for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.
pubmed:issnType
Electronic
pubmed:volume
14
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
e444-7
pubmed:dateRevised
2010-10-22
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Progressive multifocal leukoencephalopathy in a patient with Good's syndrome.
pubmed:affiliation
Neurology Unit, Ospedale Civile Maggiore, Piazzale Stefani, 1, 37134, Verona, Italy. neurogio@tiscali.it
pubmed:publicationType
Journal Article, Case Reports