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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
2009-9-3
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pubmed:abstractText |
Activating mutations in the epidermal growth factor receptor gene (EGFR) confer hypersensitivity to the tyrosine kinase inhibitors gefitinib and erlotinib in patients with advanced non-small-cell lung cancer. We evaluated the feasibility of large-scale screening for EGFR mutations in such patients and analyzed the association between the mutations and the outcome of erlotinib treatment.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1533-4406
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pubmed:author |
pubmed-author:BastusRomanR,
pubmed-author:Bertran-AlamilloJordiJ,
pubmed-author:BoverIsabelI,
pubmed-author:CampsCarlosC,
pubmed-author:CardenalFelipeF,
pubmed-author:CatotSilviaS,
pubmed-author:Garcia-CampeloRosarioR,
pubmed-author:Gonzalez-LarribaJose LuisJL,
pubmed-author:InsaAmeliaA,
pubmed-author:IslaDoloresD,
pubmed-author:Lopez-VivancoGuillermoG,
pubmed-author:MajemMargaritaM,
pubmed-author:MassutiBartomeuB,
pubmed-author:MayoClaraC,
pubmed-author:MolinaMiguel AngelMA,
pubmed-author:MoranTeresaT,
pubmed-author:MorenoMiguel AngelMA,
pubmed-author:PalmeroRamonR,
pubmed-author:Paz-AresLuisL,
pubmed-author:PortaRutR,
pubmed-author:ProvencioMarianoM,
pubmed-author:QueraltCristinaC,
pubmed-author:ReguartNoemiN,
pubmed-author:RolfoChristianC,
pubmed-author:RosellRafaelR,
pubmed-author:SánchezJosé MiguelJM,
pubmed-author:SanchezJose JavierJJ,
pubmed-author:Spanish Lung Cancer Group,
pubmed-author:TaronMiquelM
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pubmed:copyrightInfo |
2009 Massachusetts Medical Society
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pubmed:issnType |
Electronic
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pubmed:day |
3
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pubmed:volume |
361
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
958-67
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:19692684-Adult,
pubmed-meshheading:19692684-Aged,
pubmed-meshheading:19692684-Aged, 80 and over,
pubmed-meshheading:19692684-Carcinoma, Non-Small-Cell Lung,
pubmed-meshheading:19692684-Diarrhea,
pubmed-meshheading:19692684-Exanthema,
pubmed-meshheading:19692684-Female,
pubmed-meshheading:19692684-Humans,
pubmed-meshheading:19692684-Kaplan-Meier Estimate,
pubmed-meshheading:19692684-Lung Neoplasms,
pubmed-meshheading:19692684-Male,
pubmed-meshheading:19692684-Middle Aged,
pubmed-meshheading:19692684-Multivariate Analysis,
pubmed-meshheading:19692684-Mutation,
pubmed-meshheading:19692684-Prospective Studies,
pubmed-meshheading:19692684-Protein Kinase Inhibitors,
pubmed-meshheading:19692684-Quinazolines,
pubmed-meshheading:19692684-Receptor, Epidermal Growth Factor,
pubmed-meshheading:19692684-Sex Distribution,
pubmed-meshheading:19692684-Survival Analysis,
pubmed-meshheading:19692684-Young Adult
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pubmed:year |
2009
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pubmed:articleTitle |
Screening for epidermal growth factor receptor mutations in lung cancer.
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pubmed:affiliation |
Catalan Institute of Oncology and Autonomous University of Barcelona, Hospital Germans Trias i Pujol, Barcelona, Spain.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Multicenter Study,
Evaluation Studies
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