Linked Life Data

19692607

Source:http://linkedlifedata.com/resource/pubmed/id/19692607

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
33
pubmed:dateCreated
2009-8-20
pubmed:abstractText
It is widely held that long-term memory gradually develops in the temporal neocortex after initial memory encoding into the hippocampus. However, little is known as to whether and where long-term memory can be newly created in the human temporal neocortex. In this functional magnetic resonance imaging study, we detected brain activity in the temporal neocortex that was developed approximately 8 weeks after study of unfamiliar pictorial paired associates. Two sets of paired Fourier figures were studied, one approximately 8 weeks before test and the other immediately before test, keeping the correct performance during the tests balanced across the two sets of stimuli. Significant signal increase was observed in the right hippocampus during retrieval of newly studied pairs relative to initially studied pairs. In contrast, significant signal increase was observed in the anterior temporal cortex during retrieval of initially studied pairs relative to newly studied pairs. The greater activity during retrieval of older memory developed in the temporal neocortex provides direct evidence of formation of temporal neocortical representation for stable long-term memory.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
1529-2401
pubmed:author
pubmed:issnType
Electronic
pubmed:day
19
pubmed:volume
29
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
10335-40
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Formation of long-term memory representation in human temporal cortex related to pictorial paired associates.
pubmed:affiliation
Department of Physiology and Radiology, The University of Tokyo School of Medicine, Tokyo, Japan.
pubmed:publicationType
Journal Article, Comparative Study