Source:http://linkedlifedata.com/resource/pubmed/id/19692422
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2009-8-31
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pubmed:abstractText |
Rapid bioassay is very important for immediate and near-term consequence management, which includes identifying contaminated individuals and providing necessary medical intervention during a radiological or nuclear emergency. This paper reports the application of a newly developed bioassay technique for (90)Sr in urine on a field deployable instrument, the Triathler. Performance of this field technique for sensitivity, accuracy and repeatability is evaluated against bioassay criteria (ANSI N13.30). This field technique offers the following analytical merits: (1) minimum detectable activity of 121 Bq l(-1) when 20 ml of urine is used; (2) relative bias of 11.1 % and relative precision of 3.2 % at the level of 45 Bq per 20 ml of urine and (3) sample turnaround time of less than 1 h. The technique meets the requirements for emergency bioassay when a committed effective dose of 0.5 Sv is used as the action dose threshold for medical intervention. Sample throughput can be significantly improved if this technique is automated.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1742-3406
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
136
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
82-6
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pubmed:dateRevised |
2010-11-10
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pubmed:meshHeading |
pubmed-meshheading:19692422-Adult,
pubmed-meshheading:19692422-Biological Assay,
pubmed-meshheading:19692422-Humans,
pubmed-meshheading:19692422-Radiation Monitoring,
pubmed-meshheading:19692422-Sensitivity and Specificity,
pubmed-meshheading:19692422-Strontium Radioisotopes,
pubmed-meshheading:19692422-Urinalysis,
pubmed-meshheading:19692422-Urine
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pubmed:year |
2009
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pubmed:articleTitle |
Field deployable technique for 90Sr emergency bioassay.
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pubmed:affiliation |
Radiation Protection Bureau, Health Canada, Ottawa, ON, Canada. li_chunsheng@hc-sc.gc.ca
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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