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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
12
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pubmed:dateCreated |
2009-11-30
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pubmed:abstractText |
Identifying susceptibility genes for endophenotypes by studying analogous behaviors across species is an important strategy for understanding the pathophysiology underlying psychiatric disorders. This approach provides novel biological pathways plus validated animal models critical for selective drug development. One such endophenotype is avoidance behavior.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1873-2402
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
15
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pubmed:volume |
66
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1123-30
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pubmed:meshHeading |
pubmed-meshheading:19691954-Adenylate Cyclase,
pubmed-meshheading:19691954-Animals,
pubmed-meshheading:19691954-Chromosome Mapping,
pubmed-meshheading:19691954-Chromosomes, Mammalian,
pubmed-meshheading:19691954-Escape Reaction,
pubmed-meshheading:19691954-Female,
pubmed-meshheading:19691954-Gene Expression Profiling,
pubmed-meshheading:19691954-Genetic Predisposition to Disease,
pubmed-meshheading:19691954-Genotype,
pubmed-meshheading:19691954-Humans,
pubmed-meshheading:19691954-KCNQ3 Potassium Channel,
pubmed-meshheading:19691954-Mice,
pubmed-meshheading:19691954-Mice, Inbred C57BL,
pubmed-meshheading:19691954-Mice, Transgenic,
pubmed-meshheading:19691954-Models, Genetic,
pubmed-meshheading:19691954-Mood Disorders,
pubmed-meshheading:19691954-Motor Activity,
pubmed-meshheading:19691954-Oligonucleotide Array Sequence Analysis,
pubmed-meshheading:19691954-Phenotype,
pubmed-meshheading:19691954-Polymorphism, Single Nucleotide,
pubmed-meshheading:19691954-Quantitative Trait Loci
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pubmed:year |
2009
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pubmed:articleTitle |
Interspecies trait genetics reveals association of Adcy8 with mouse avoidance behavior and a human mood disorder.
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pubmed:affiliation |
Rudolf Magnus Institute of Neuroscience, Department of Neuroscience and Pharmacology, University Medical Centre Utrecht, 3584 CG Utrecht, The Netherlands.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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