Source:http://linkedlifedata.com/resource/pubmed/id/19688022
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2009-8-18
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pubmed:abstractText |
Patients with diabetes mellitus type II suffer from hyperglycemia because they are not able to use the insulin that they produce, often due to inadequate function of insulin receptors. There are some evidences that this deficiency is inherited in a dominant autosomal manner and leads to the malfunction of the pancreatic beta cells resulting in insulin excretion disorders. In this study, we sought to identify mutations in the insulin receptor (INSR) gene, which can cause insulin resistance in type II diabetic patients.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1028-852X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
13
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
161-8
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pubmed:meshHeading |
pubmed-meshheading:19688022-Adult,
pubmed-meshheading:19688022-Aged,
pubmed-meshheading:19688022-Aged, 80 and over,
pubmed-meshheading:19688022-Base Sequence,
pubmed-meshheading:19688022-Case-Control Studies,
pubmed-meshheading:19688022-DNA Mutational Analysis,
pubmed-meshheading:19688022-Diabetes Mellitus, Type 2,
pubmed-meshheading:19688022-Geography,
pubmed-meshheading:19688022-Humans,
pubmed-meshheading:19688022-Iran,
pubmed-meshheading:19688022-Middle Aged,
pubmed-meshheading:19688022-Mutation,
pubmed-meshheading:19688022-Receptor, Insulin
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pubmed:year |
2009
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pubmed:articleTitle |
Insulin receptor gene mutations in iranian patients with type II diabetes mellitus.
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pubmed:affiliation |
Cellular and Molecular Biology Research Center, Shahid Beheshti University, MC, Tehran, Iran. bahram_14@yahoo.com
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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