Linked Life Data

19687594

Source:http://linkedlifedata.com/resource/pubmed/id/19687594

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
16
pubmed:dateCreated
2009-8-18
pubmed:abstractText
Biphenotypic acute leukemia (BAL) is a rare entity that comprises 0.5-3% of all acute leukemias and probably arises from multipotent progenitor cells. The optimal approach for BAL therapy is unknown. Thus, it is important to elucidate the origin of the neoplastic cells for determination of the appropriate therapy. We report the case of a 41-year-old man with BAL having myeloid and T-lymphoid lineage phenotypes. Strangely, neither CD34 nor TdT expression nor rearrangement of TCR-alpha/beta, delta/gamma genes were shown. This pattern is rarely encountered and suggests that the blast cells were possibly considered immature with aspects of differentiation indicating myeloid lineage, rather than T-lymphoid lineage.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1349-7235
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
48
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1437-41
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Acute leukemia of ambiguous lineage, biphenotype, without CD34, TdT or TCR-rearrangement.
pubmed:affiliation
Division of Hematology, Department of Internal Medicine, Faculty of Medicine, Kagawa University. t111nishiuchi@yahoo.co.jp
pubmed:publicationType
Journal Article, Case Reports