Source:http://linkedlifedata.com/resource/pubmed/id/19683841
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
12
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pubmed:dateCreated |
2009-11-25
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pubmed:abstractText |
A novel series of 1,4-bis(6-(substituted phenyl)-[1,2,4]-triazolo[3,4-b]-1,3,4-thiadiazoles (5a-b) and 4-bis(substituted phenyl)-4-thiazolidinone derivatives (7a-c) have been synthesized from terephthalic dihydrazide (1) through multistep reaction sequence. 1,4-Bis(5-aryl-1,3,4-oxadiazole-2yl) benzene derivatives (2a-f) and bis-substituted terephthalohydrazide (6a-e) were also synthesized from terephthalic dihydrazide by cyclization with various aromatic acids and aldehydes. Terephthalic dihydrazide (1) was obtained from poly(ethylene terephthalate) waste from reaction with hydrazine hydrate in good yield (86%). All the synthesized compounds were screened for their antibacterial activities against various bacteria and fungi strains. Several of these compounds showed potential antibacterial activity.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Anti-Bacterial Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Hydrazines,
http://linkedlifedata.com/resource/pubmed/chemical/Oxadiazoles,
http://linkedlifedata.com/resource/pubmed/chemical/Phthalic Acids,
http://linkedlifedata.com/resource/pubmed/chemical/Thiadiazoles,
http://linkedlifedata.com/resource/pubmed/chemical/hydrazine,
http://linkedlifedata.com/resource/pubmed/chemical/terephthalic acid
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1768-3254
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
44
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
5112-6
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pubmed:meshHeading |
pubmed-meshheading:19683841-Anti-Bacterial Agents,
pubmed-meshheading:19683841-Hydrazines,
pubmed-meshheading:19683841-Microbial Sensitivity Tests,
pubmed-meshheading:19683841-Molecular Structure,
pubmed-meshheading:19683841-Oxadiazoles,
pubmed-meshheading:19683841-Phthalic Acids,
pubmed-meshheading:19683841-Thiadiazoles
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pubmed:year |
2009
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pubmed:articleTitle |
Synthesis and antibacterial activity of some novel bis-1,2,4-triazolo[3,4-b]-1,3,4-thiadiazoles and bis-4-thiazolidinone derivatives from terephthalic dihydrazide.
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pubmed:affiliation |
Department of Fibres and Textile Processing Technology, Institute of Chemical Technology (Autonomous), University of Mumbai, N. Parekh Marg, Matunga, Mumbai 400019, Maharashtra, India.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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